3-Isopropylidene-2,3-dihydro-benzo[b]thiophene 1,1-dioxide | 37602-54-3

• 分子结构分类: 有机化合物 - 苯类化合物
• 英文名称: 3-Isopropylidene-2,3-dihydro-benzo[b]thiophene 1,1-dioxide
• 英文别名: 3-Propan-2-ylidene-1-benzothiophene 1,1-dioxide
• CAS: 37602-54-3
• 化学式: C₁₁H₁₂O₂S
• 分子量: 208.281
• InChiKey: QGWWLJIUCCRPCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• IL-12 MODULATORY COMPOUNDS
  申请人：Demko Zachary

  公开号：US20110294798A1

  公开（公告）日：2011-12-01

  The invention relates to cyclic hydrazone compounds, compositions including the cyclic hydrazone compounds and methods of using and methods of making thereof. The compounds (and compositions) are useful, inter alia, in modulating IL-12 production and processes mediated by IL-12.

  本发明涉及循环腙类化合物、包括循环腙类化合物的组合物以及使用和制备它们的方法。该化合物（和组合物）可用于调节IL-12的产生和由IL-12介导的过程，因此具有实用价值。
• Method for treating B cell regulated autoimmune disorders
  申请人：Foley Kevin

  公开号：US20070032493A1

  公开（公告）日：2007-02-08

  The invention relates to a method for treating B-cell regulated autoimmune disorders using compounds that modulate the activity of c-Rel.
• PROCESS FOR PREPARING MESYLATE SALTS OF IL-12 INHIBITORY COMPOUNDS
  申请人：Kostik Elena

  公开号：US20090163708A1

  公开（公告）日：2009-06-25

  This invention relates to a method of preparing mesylate salts of compounds that inhibit IL-12, IL-23 and/or IL-27 production.
• TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS
  申请人：Babu Suresh R.

  公开号：US20110098267A1

  公开（公告）日：2011-04-28

  The invention relates to a topical composition and a method for treating psoriasis. The topical composition comprises one or more compound that inhibits the production of IL-12 and IL-23.
• METHOD FOR TREATING B CELL REGULATED AUTOIMMUNE DISORDERS
  申请人：Foley Kevin

  公开号：US20120021434A1

  公开（公告）日：2012-01-26

  The invention relates to a method for treating B-cell regulated autoimmune disorders using compounds that modulate the activity of c-Rel.