Paracetamol monohydrate | 495388-37-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Paracetamol monohydrate
• 英文别名: N-(4-hydroxyphenyl)acetamide;hydrate
• CAS: 495388-37-9
• 化学式: C8H11NO3
• 分子量: 169.18
• InChiKey: YRYDDQRIBSKYPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.53
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  50.3
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• [EN] PHARMACEUTICAL COMBINATION CONTAINING GLUCOSAMINE SALTS AND PARACETAMOL FOR THE TREATMENT OF OSTEOARTHRITIS<br/>[FR] ASSOCIATION PHARMACEUTIQUE CONTENANT DES SELS DE GLUCOSAMINE ET DU PARACÉTAMOL POUR LE TRAITEMENT DE L'ARTHROSE
  申请人：ABDI IBRAHIM ILAC SANAYYI VE TICARET ANONIM SIRKETI

  公开号：WO2012095726A1

  公开（公告）日：2012-07-19

  This invention relates to a pharmaceutical composition comprising a combination of glucosamine or its pharmaceutically acceptable salts (preferably glucosamine sulphate or glucosamine hydrochloride) and paracetamol for decreasing pain while simultaneously improving joint movement, for the treatment of osteoarthritis. This invention also relates to kits containing a pharmaceutical combination of: a) therapeutically effective amount of glucosamine or its pharmaceutically acceptable salts and b) therapeutically effective amount of paracetamol to treat patients suffering from osteoarthritis, as well as the production method of such combination.