bis(N-2,6-dichlorobenzylimidazol-2-yl)methane | 702687-80-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(N-2,6-dichlorobenzylimidazol-2-yl)methane
• 英文别名: 1-[(2,6-Dichlorophenyl)methyl]-2-[[1-[(2,6-dichlorophenyl)methyl]imidazol-2-yl]methyl]imidazole
• CAS: 702687-80-7
• 化学式: C₂₁H₁₆Cl₄N₄
• 分子量: 466.197
• InChiKey: WQLGOBRNPJKXQP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  35.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  bis(N-2,6-dichlorobenzylimidazol-2-yl)methane 、 silver perchlorate 以 甲醇 为溶剂， 以57%的产率得到[Ag2(bis(N-2,6-dichlorobenzylimidazol-2-yl)methane)2](perchlorate)2
  参考文献：
  名称：

  Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidazole ligands

  摘要：

  ;ive Ag(I) complexes containing the ligands bis(imidazol-2-yl)methane (2-BIM) and its derivatives were prepared and [Ag-2(2-BIM)(2)](ClO4)(2) and [Ag-2(2-BIM(Bz)OH)(2)](ClO4)(2) . EtOH were characterised using X-ray crystallography. In each dimer the two Ag(I) ions are two-coordinate and there are small but definite argentophilic Ag-Ag (d(10)-d(10)) interactions. All of the complexes display anti-fungal activity when tested in vitro against the fungal pathogen Candida albicans. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2004.02.006