4-chlorobenzyl-triethylphosphonium bromide | 1238861-71-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-chlorobenzyl-triethylphosphonium bromide
• CAS: 1238861-71-6
• 化学式: Br*C₁₃H₂₁ClP
• 分子量: 323.64
• InChiKey: DPGNWEDETNDTEF-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.92
• 重原子数：
  16.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  4-chlorobenzyl-triethylphosphonium bromide 、 对羟基甲基苯甲醛 在 lithium hydroxide 作用下， 以 水 为溶剂， 反应 3.55h， 生成
  参考文献：
  名称：

  An iterative approach toward the synthesis of discrete oligomeric p-phenylene vinylene organic dyes employing aqueous Wittig chemistry

  摘要：

  Photovoltaic research has become increasingly prominent as the search for alternatives to fossil fuels are actively sought. A novel process for the iterative synthesis of discrete donor/acceptor-flanked oligostilbenes, key constituents in dye-sensitized solar cells, is described. The aqueous Wittig process is high yielding, proceeds with high (E)-stereoselectivity and allows facile product purification. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.040
• 作为产物：
  描述：

  triethylphosphonium hydrochloride 、 4-氯苯甲醇 反应 8.0h， 生成 4-chlorobenzyl-triethylphosphonium bromide
  参考文献：
  名称：

  An iterative approach toward the synthesis of discrete oligomeric p-phenylene vinylene organic dyes employing aqueous Wittig chemistry

  摘要：

  Photovoltaic research has become increasingly prominent as the search for alternatives to fossil fuels are actively sought. A novel process for the iterative synthesis of discrete donor/acceptor-flanked oligostilbenes, key constituents in dye-sensitized solar cells, is described. The aqueous Wittig process is high yielding, proceeds with high (E)-stereoselectivity and allows facile product purification. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.040

文献信息

• Microwave-Assisted, Aqueous Wittig Reactions: Organic-Solvent- and Protecting-Group-Free Chemoselective Synthesis of Functionalized Alkenes
  作者：James McNulty、Priyabrata Das、David McLeod

  DOI：10.1002/chem.201000438

  日期：——

  Free from protection! A general, chemoselective, protecting‐group‐ and organic‐solvent‐free route to stilbenes and heterostilbenes involving the direct synthesis of triethyl benzylic and allylic phosphonium salts from the corresponding alcohols and their microwave‐assisted, aqueous Wittig reactions is described.

  不受保护！描述了一种通用的，化学选择性的，无保护基团和无有机溶剂的方法，可合成出对til苯甲醛和异对til苯甲醛，涉及从相应的醇直接合成三乙基苄基和烯丙基phospho盐及其微波辅助的Wittig水溶液反应。
• A direct synthesis of functionalized styrenes and terminal 1,3-dienes via aqueous Wittig chemistry with formalin
  作者：Priyabrata Das、David McLeod、James McNulty

  DOI：10.1016/j.tetlet.2010.10.090

  日期：2011.1

  A direct synthesis of functionalized styrenes including synthetically valuable styryl halides and terminal 1,3-dienes is reported directly from benzylic and allylic alcohols and aqueous formalin involving microwave assisted phosphonium salt formation and Wittig olefination under mildly basic conditions. (C) 2010 Elsevier Ltd. All rights reserved.