N-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | 1281860-87-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三唑并嘧啶类
• 英文名称: N-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
• 英文别名: DSM219；N-(5,6-dimethoxyindan-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
• CAS: 1281860-87-4
• 化学式: C₁₇H₁₉N₅O₂
• 分子量: 325.37
• InChiKey: BXYKXHQSNDQXCS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  73.6
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• NON-AQUEOUS ELECTROLYTIC SOLUTION, ELECTROCHEMICAL ELEMENT USING SAME, AND ALKYNYL COMPOUND USED THEREFOR
  申请人：Abe Koji

  公开号：US20120301797A1

  公开（公告）日：2012-11-29

  The present invention provides an excellent nonaqueous electrolytic solution capable of improving low-temperature and high-temperature cycle properties and load characteristics after high-temperature charging storage, an electrochemical element using it, and an alkynyl compound used for it. The nonaqueous electrolytic solution of the present invention comprises containing at least one alkynyl compound represented by the following general formula (I) in an amount of from 0.01 to 10% by mass in the nonaqueous electrolytic solution. R 1 (O) n —X 1 —R 2 (I) (In the formula, X 1 represents a group —C(═O)—, a group —C(═O)—C(═O)—, a group —S(═O) 2 —, a group —P(═O) (—R 3 )—, or a group —X 2 —S(═O) 2 O—. R 1 represents an alkenyl group, a formyl group, an alkyl group, an acyl group, an arylcarbonyl, an alkanesulfonyl group, an alkynyloxysulfonyl group, an arylsulfonyl group, a dialkylphosphoryl group, an alkyl(alkoxy)phosphoryl group, or a dialkoxyphosphoryl group; R 2 represents an alkynyl group or an alkynyloxy group; R 3 represents an alkyl group, an alkenyl group, an alkynyl group, an aryl group, an alkoxy group, an alkenyloxy group, an alkynyloxy group, or an aryloxy group; n indicates 0 or 1.

  本发明提供了一种优秀的非水电解质溶液，能够改善低温和高温循环性能以及高温充电存储后的负载特性，以及使用它的电化学元件和用于它的炔基化合物。本发明的非水电解质溶液包括以下通式（I）表示的至少一种炔基化合物，其在非水电解质溶液中的质量分数为0.01至10%。R1（O）n—X1—R2（I）（在式中，X1表示基团—C(═O)—，基团—C(═O)—C(═O)—，基团—S(═O)2—，基团—P(═O)(—R3)—，或基团—X2—S(═O)2O—。R1表示烯基基团，甲酰基团，烷基基团，酰基团，芳基羰基，烷烷基磺酰基，炔氧基磺酰基，芳基磺酰基，二烷基磷酰基，烷基(烷氧基)磷酰基，或二烷氧基磷酰基；R2表示炔基团或炔氧基团；R3表示烷基，烯基，炔基，芳基，烷氧基，烯氧基，炔氧基，或芳氧基；n表示0或1。
• ANTIMALARIAL AGENTS THAT ARE INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE
  申请人：Rathod Pradipsinh K.

  公开号：US20120302586A1

  公开（公告）日：2012-11-29

  Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.

  抑制寄生虫脱氢酶酶（DHOD）的药物是治疗疟疾的候选治疗药物。这类治疗药物的例子包括化合物：以及符合公式IX的三唑嘧啶类化合物及其溶剂化物、立体异构体、互变异构体和药学上可接受的盐。
• Non-aqueous electrolytic solution, electrochemical element using the same and alkynyl compound used therefor
  申请人：Ube Industries, Ltd.

  公开号：EP2883867A2

  公开（公告）日：2015-06-17

  The present invention provides an excellent nonaqueous electrolytic solution capable of improving low-temperature and high-temperature cycle properties and load characteristics after high-temperature charging storage, an electrochemical element using it, and an alkynyl compound used for it. The nonaqueous electrolytic solution of the present invention comprises at least one alkynyl compound represented by the following general formula (I) in an amount of from 0.01 to 10% by mass in the nonaqueous electrolytic solution.          R1(O)n-X1-R2     (I) In the formula, X1 represents a group -C(=O)-, a group -S(=O)2-, or a group -P(=O)(-R3)-. R1 represents an alkenyl group having from 2 to 8 carbon atoms; R2 represents an alkynyl group having from 3 to 8 carbon atoms or an alkynyloxy group having from 3 to 8 carbon atoms; R3 represents an alkyl group, an alkenyl group, an alkynyl group, an aryl group, an alkoxy group, an alkenyloxy group, an alkynyloxy group, or an aryloxy group; n indicates 0 or 1.

  本发明提供了一种能够改善低温和高温循环特性以及高温充电储存后负载特性的优良非水基电解溶液、使用该溶液的电化学元件以及用于该溶液的炔基化合物。 本发明的非水基电解溶液包含至少一种由下式通式（I）表示的炔基化合物，其在非水基电解溶液中的含量为 0.01 至 10%（按质量计）。 R1(O)n-X1-R2 (I) 式中，X1 代表基团-C(=O)-、基团-S(=O)2-或基团-P(=O)(-R3)-。R1 代表具有 2 至 8 个碳原子的烯基；R2 代表具有 3 至 8 个碳原子的炔基或具有 3 至 8 个碳原子的炔氧基；R3 代表烷基、烯基、炔基、芳基、烷氧基、烯氧基、炔氧基或芳氧基；n 表示 0 或 1。
• Non-aqueous electrolytic solution and electrochemical element using the same
  申请人：Ube Industries, Ltd.

  公开号：EP2883867B1

  公开（公告）日：2017-06-28
• NON-AQUEOUS ELECTROLYTIC SOLUTION, ELECTROCHEMICAL ELEMENT USING THE SAME, AND ALKYNYL COMPOUND USED THEREFOR
  申请人：Ube Industries, Ltd.

  公开号：EP2533344B1

  公开（公告）日：2016-07-20