Acetylene--pyridine (1/1) | 790665-58-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Acetylene--pyridine (1/1)
• 英文别名: acetylene;pyridine
• CAS: 790665-58-6
• 化学式: C7H7N
• 分子量: 105.14
• InChiKey: HFJASQBEIMATBQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.33
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] BENZENE SULFONAMIDES AS CCR9 INHIBITORS<br/>[FR] BENZÈNE-SULFONAMIDES À TITRE D'INHIBITEURS DE CCR9
  申请人：NORGINE BV

  公开号：WO2015097122A1

  公开（公告）日：2015-07-02

  The present invention relates to compounds useful as CCR9 modulators, to compositions containing them, to methods of making them, and to methods of using them. In particular, the present invention relates to compounds capable of modulating the function of the CCR9 receptor by acting as partial agonists, antagonists or inverse agonists. Such compounds may be useful to treat, prevent or ameliorate a disease or condition associated with CCR9 activation, including inflammatory and immune disorder diseases or conditions such as inflammatory bowel diseases (IBD).

  本发明涉及作为CCR9调节剂有用的化合物，包含这些化合物的组合物，制备它们的方法，以及使用它们的方法。具体而言，本发明涉及能够通过作为部分激动剂、拮抗剂或逆激动剂来调节CCR9受体功能的化合物。这些化合物可能有助于治疗、预防或缓解与CCR9激活相关的疾病或状况，包括炎症和免疫性疾病或状况，如炎症性肠病（IBD）。
• [EN] COSMETIC COMPOSITION COMPRISING AT LEAST ONE SPECIFIC BLOCK COPOLYMER<br/>[FR] COMPOSITION COSMÉTIQUE COMPRENANT AU MOINS UN COPOLYMÈRE SPÉCIFIQUE SÉQUENCÉ
  申请人：OREAL

  公开号：WO2005110350A1

  公开（公告）日：2005-11-24

  The present invention relates to a cosmetic composition comprising, in a physiologically acceptable medium: at least one fatty phase, and at least one block copolymer of rod-coil type comprising at least one coil polymeric block structure with a variable conformation covalently bonded to at least one rod polymeric block structure with a restricted conformation.

  本发明涉及一种化妆品组合物，包括在生理可接受的介质中：至少一种脂肪相，以及至少一种由至少一个具有可变构象的卷曲聚合物块结构与至少一个具有受限构象的杆状聚合物块结构共价键合的杆卷型嵌段共聚物。
• [EN] COSMETIC COMPOSITION COMPRISING AT LEAST ONE SPECIFIC BLOCK COPOLYMER<br/>[FR] COMPOSITION COSMETIQUE COMPRENANT AU MOINS UN COPOLYMERE SEQUENCE SPECIFIQUE
  申请人：OREAL

  公开号：WO2005110351A1

  公开（公告）日：2005-11-24

  The present invention relates to a cosmetic composition comprising, in a physiologically acceptable medium: at least one aqueous phase, at least one preservative, and at least one block copolymer of rod-coil type comprising at least one coil polymeric block structure with a variable conformation covalently bonded to at least one rod polymeric block structure with a restricted conformation.

  本发明涉及一种化妆品组合物，包括以下成分，均在生理上可接受的介质中：至少一种水相，至少一种防腐剂，以及至少一种由至少一个线性高分子块结构和至少一个限制构象的杆状高分子块结构共价键合而成的线-卷型嵌段共聚物。
• COSMETIC COMPOSITION COMPRISING AT LEAST ONE SPECIFIC BLOCK COPOLYMER
  申请人：L'ORÉAL

  公开号：EP1744722A1

  公开（公告）日：2007-01-24
• BENZENE SULFONAMIDES AS CCR9 INHIBITORS
  申请人：Norgine BV

  公开号：EP3087074A1

  公开（公告）日：2016-11-02