I+/--(1-Ethylpropyl)benzeneacetic acid | 14381-59-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: I+/--(1-Ethylpropyl)benzeneacetic acid
• 英文别名: 3-ethyl-2-phenylpentanoic acid
• CAS: 14381-59-0
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.28
• InChiKey: FJOBGMYNAZCGSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS
  申请人：Stewart Andrew O.

  公开号：US20100130558A1

  公开（公告）日：2010-05-27

  The present application relates to calcium channel inhibitors containing compounds of formula (I) wherein L 1 , L 2 , R 1 , R 2 , and R 3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

  本申请涉及含有式（I）化合物的钙通道抑制剂，其中L1、L2、R1、R2和R3如规范中所定义。本申请还涉及包含这种化合物的组合物，以及使用这种化合物和组合物治疗疾病和疾病的方法。
• SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS
  申请人：Abbott Laboratories

  公开号：EP2367790A2

  公开（公告）日：2011-09-28
• US8129417B2
  申请人：——

  公开号：US8129417B2

  公开（公告）日：2012-03-06
• [EN] NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS<br/>[FR] NOUVELLES OCTAHYDROCYLOPENTA(C)PYRROL-4-AMINES SUBSTITUÉES EN TANT QUE BLOQUEURS DES CANAUX CALCIQUES
  申请人：ABBOTT LAB

  公开号：WO2010062927A2

  公开（公告）日：2010-06-03

  The present application relates to calcium channel inhibitors containing compounds of formula (I), wherein L1, L2, R1, R2, and R3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
• [EN] NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA [C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS<br/>[FR] NOUVELLES OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES SUBSTITUÉES COMME BLOQUEURS DE CANAUX CALCIQUES
  申请人：ABBOTT LAB

  公开号：WO2011149995A1

  公开（公告）日：2011-12-01

  The present application relates to calcium channel inhibitors containing compounds of formula (I) wherein L1, L2, R1, R2, and R3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.