N-cyclopropyl-4-[[(2-chlorobenzoyl)amino]sulfonyl]benzamide | 221667-33-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-cyclopropyl-4-[[(2-chlorobenzoyl)amino]sulfonyl]benzamide
• 英文别名: 2-chloro-N-[4-(cyclopropylcarbamoyl)phenyl]sulfonylbenzamide
• CAS: 221667-33-0
• 化学式: C₁₇H₁₅ClN₂O₄S
• 分子量: 378.836
• InChiKey: DJANJHJIGZZPEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  101
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Process for preparing acylsulfamoylbenzamides
  申请人：Pazenok Sergiy

  公开号：US20050004372A1

  公开（公告）日：2005-01-06

  The invention relates to a process for the preparation of a compound of formula (I): Which comprises reaction of a compound of formula (II) with a compound of the formula (III) in the presence of a chlorinating agent, followed by reaction of the resultant compound of the formula (IV) with a compound of formula (V) in the presence of a base: wherein the various symbols are as defined in claim 1.

  本发明涉及一种制备式(I)化合物的方法，该方法包括在氯化剂存在下使式(II)化合物与式(III)化合物反应，然后在碱存在下使所得的式(IV)化合物与式(V)化合物反应，其中各符号如权利要求1所定义。
• PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES
  申请人：PAZENOK Sergiy

  公开号：US20100094052A1

  公开（公告）日：2010-04-15

  The invention relates to a process for the preparation of a compound of formula (I): Which comprises reaction of a compound of formula (II) with a compound of the formula (III) in the presence of a chlorinating agent, followed by reaction of the resultant compound of the formula (IV) with a compound of formula (V) in the presence of a base: wherein the various symbols are as defined in claim 1.

  本发明涉及一种制备公式(I)化合物的方法，包括在氯化剂存在下，将公式(II)化合物与公式(III)化合物反应，然后在碱存在下，将所得的公式(IV)化合物与公式(V)化合物反应，其中各种符号如权利要求1所定义。
• US7608736B2
  申请人：——

  公开号：US7608736B2

  公开（公告）日：2009-10-27
• US8236986B2
  申请人：——

  公开号：US8236986B2

  公开（公告）日：2012-08-07
• [EN] PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES<br/>[FR] PROCEDE DE PREPARATION D'ACYLSULFAMOYLBENZAMIDES
  申请人：BAYER CROPSCIENCE GMBH

  公开号：WO2005000797A1

  公开（公告）日：2005-01-06

  The invention relates to a process for the preparation of a compound of formula (1) which comprises reaction of a compound of formula (II) with a compound of the formula (III) in the presence of a chlorinating agent, followed by reaction of the resultant compound of the formula (IV) with a compound of formula (V) in the presence of a base wherein the various symbols are as defined in claim 1.