5-Propylpyridin-3-ol | 61893-04-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5-Propylpyridin-3-ol
• CAS: 61893-04-7
• 化学式: C₈H₁₁NO
• 分子量: 137.18
• InChiKey: LAVZJGKJJZAPBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  33.1
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• 2-AMINOQUINOLINE-BASED COMPOUNDS FOR POTENT AND SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITION
  申请人：Northwestern University

  公开号：US20150210644A1

  公开（公告）日：2015-07-30

  Various 2-aminoquinoline compounds as can be used, in vivo or in vitro, for selective inhibition of neuronal nitric oxide synthase.

  各种2-氨基喹啉化合物可用于体内或体外，选择性地抑制神经元一氧化氮合酶。
• 2-Aminoquinoline-Based Compounds for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition
  申请人：Silverman Richard B.

  公开号：US20160368877A1

  公开（公告）日：2016-12-22

  Various 2-aminoquinoline compounds as can be used, in vivo or in vitro, for selective inhibition of neuronal nitric oxide synthase.
• US9212144B2
  申请人：——

  公开号：US9212144B2

  公开（公告）日：2015-12-15
• US9783500B2
  申请人：——

  公开号：US9783500B2

  公开（公告）日：2017-10-10
• [EN] COMPOUNDS AND METHODS FOR TREATING CANCER<br/>[FR] COMPOSÉS ET MÉTHODES DE TRAITEMENT DU CANCER
  申请人：MAYO FOUNDATION

  公开号：WO2016022955A1

  公开（公告）日：2016-02-11

  This document provides compounds, compositions, and methods for treating cancers including renal cancer (e.g., renal cell carcinoma) as well as ovarian, breast, prostate, colon, pancreatic, bladder, liver, lung, and thyroid cancers and melanoma. For example, compounds, compositions, and methods for using one or more inhibitors of SCD1 to treat renal cell carcinoma (e.g., clear cell renal cell carcinoma (ccRCC)), thyroid cancer, or liver cancer; or to increase the efficacy of treatment for the same.