1,1-dinaphthalen-1-yl-N-(1-phenylbut-3-enyl)methanimine | 1174222-41-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,1-dinaphthalen-1-yl-N-(1-phenylbut-3-enyl)methanimine
• CAS: 1174222-41-3
• 化学式: C₃₁H₂₅N
• 分子量: 411.546
• InChiKey: KDELZBSYADGMME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.7
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,1-dinaphthalen-1-yl-N-(1-phenylbut-3-enyl)methanimine 在 吡啶 、 盐酸羟胺 作用下， 以 乙醇 、 水 为溶剂， 反应 0.5h， 生成 1-苯基丁-3-烯-1-基胺
  参考文献：
  名称：

  Carbon–carbon bond formations at the benzylic positions of N-benzylxanthone imines and N-benzyldi-1-naphthyl ketone imine

  摘要：

  Two N-benzyl imines are designed to allow for carbon-carbon bond formations at the aminated benzylic positions. Direct benzylic arylation reactions of N-benzylxanthone imine with aryl chlorides proceed under palladium catalysis in the presence of cesium hydroxide, yielding the corresponding benzhydrylamine derivatives. Alkylation reactions of N-benzyldi-1-naphthyl ketone imine with alkyl halides in the presence of potassium tert-butoxide afford the corresponding 1-phenylalkylamines in high yields. Conjugate addition of N-benzyldi-1-naphthyl ketone imine is also described. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.02.034
• 作为产物：
  描述：

  N-(di-1-naphthylmethylidene)benzylamine 、 3-溴丙烯 在 potassium tert-butylate 作用下， 以 四氢呋喃 为溶剂， 反应 2.67h， 以100%的产率得到1,1-dinaphthalen-1-yl-N-(1-phenylbut-3-enyl)methanimine
  参考文献：
  名称：

  Carbon–carbon bond formations at the benzylic positions of N-benzylxanthone imines and N-benzyldi-1-naphthyl ketone imine

  摘要：

  Two N-benzyl imines are designed to allow for carbon-carbon bond formations at the aminated benzylic positions. Direct benzylic arylation reactions of N-benzylxanthone imine with aryl chlorides proceed under palladium catalysis in the presence of cesium hydroxide, yielding the corresponding benzhydrylamine derivatives. Alkylation reactions of N-benzyldi-1-naphthyl ketone imine with alkyl halides in the presence of potassium tert-butoxide afford the corresponding 1-phenylalkylamines in high yields. Conjugate addition of N-benzyldi-1-naphthyl ketone imine is also described. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.02.034