This invention relates to compositions containing quaternary ammonium compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, characterized in that said composition includes at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5 %, preferably more than 7 % in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. This invention also relates to ophthalmic oil-in-water emulsions containing such compositions, said ophthalmic emulsions being useful for eye care or for the treatment of eye conditions.
本发明涉及含有季
铵盐化合物的组合物,其中氮原子被至少一个具有至少 12 个碳原子的烷基取代,其特征在于所述组合物包括占总组合物重量至少 20%的卤化
铵,其中氮原子被至少一个具有至少 14 个碳原子的烷基取代,以及占总组合物重量 5%以上,最好是 7%以上的卤化
铵,其中氮原子被至少一个具有至少 16 个碳原子的烷基取代。本发明还涉及含有此类组合物的
水包油型眼科乳剂,所述眼科乳剂可用于眼部护理或治疗眼部疾病。