Zn(O-acetylsalicylhydroxamate) * H2O | 199854-04-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Zn(O-acetylsalicylhydroxamate) * H2O
• CAS: 199854-04-1
• 化学式: C₉H₇NO₄*H₂O*Zn
• 分子量: 276.564
• InChiKey: BTVZQRBBVIHBME-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -0.08
• 重原子数：
  16.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  112.03
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  O-乙酰基水杨基氧肟酸 、 zinc(II) chloride 在 sodium hydroxide 作用下， 以 水 为溶剂， 以50%的产率得到Zn(O-acetylsalicylhydroxamate) * H2O
  参考文献：
  名称：

  Metal complexes of salicylhydroxamic acid and O-acetylsalicylhydroxamic acid

  摘要：

  The salicylhydroxamic acid (H(2)Sha) complexes, Ni(HSha)(2) . 2H(2)O, Cu(HSha)(2) . 2H(2)O, Zn(HSha)(2) . 1.5H(2)O and Fe(Sha)(3) . 2H(2)O, in which the ligand is coordinated to the metal through the hydroxamate group have been synthesised. Acetylation of salicylhydroxamic acid with acetyl chloride in pyridine gave O-acetylsalicylhydroxamic acid (H(2)Sha-OAc) in which the hydroxamate oxygen is acetylated and from which the complexes Ni(HSha-OAc)(2) . H2O and Zn(Sha-OAc) were prepared. In the zinc complex the ligand is coordinated to the metal through the phenolate oxygen and the deprotonated nitrogen of the acetylhydroxamic group, the latter being an extremely rare type of coordination in the case of this metal ion. Attempted preparation of iron(III) and copper(II) complexes resulted in deacetylation of the ligand and the formation of salicylhydroxamate complexes. (C) 1997 Elsevier Science S.A.

  DOI：

  10.1016/s0020-1693(97)05536-9