| 1193357-33-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1193357-33-3
• 化学式: C₃₉H₄₃Br₂F₃O₇
• 分子量: 840.569
• InChiKey: GZZSEITZOPQUEH-OYZWTNLISA-N

反应信息

• 作为产物：
  描述：

  、 甲氧基-三氟甲基苯 在 吡啶 作用下， 反应 16.0h， 生成
  参考文献：
  名称：

  Cytotoxic eremophilane sesquiterpenoids from the saprobic fungus Berkleasmium nigroapicale BCC 8220

  摘要：

  Berkleasmins A-E, five new eremophilane sesquiterpenoids were isolated from the saprobic fungus Berkleasmium nigroapicale BCC 8220. The structures of the new compounds were elucidated by analyses of NMR spectroscopic and mass spectrometry data in combination with chemical means. Berkleasmins A and C exhibited cytotoxic activity against cancer cell-lines (NCI-H187, MCF-7, and KB) as well as nonmalignant Vero cells with IC(50) values of 1.1-7.5 mu g/mL, and these compounds also showed antimalarial activity with respective IC(50) of 3.1 and 2.8 mu g/mL. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.08.077