[2S-[2alpha,5alpha,6beta(S*)]]-6-(2,2-二甲基-5-氧代-4-苯基咪唑烷-1-基)-3,3-二甲基-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸钠 | 54450-67-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 中文名称: [2S-[2alpha,5alpha,6beta(S*)]]-6-(2,2-二甲基-5-氧代-4-苯基咪唑烷-1-基)-3,3-二甲基-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸钠
• CAS: 54450-67-8
• 化学式: C19H23N3NaO4S
• 分子量: 412.5
• InChiKey: YQSVNRMAEMOFRH-XFAPPKAWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.03
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  115
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Preparation for external use comprising an ionic liquid
  申请人：NITTO DENKO CORPORATION

  公开号：EP1795188B1

  公开（公告）日：2010-03-31
• External preparation
  申请人：Washiro Satoko

  公开号：US20070134311A1

  公开（公告）日：2007-06-14

  An external preparation having excellent percutaneous absorption ability for ionic drugs is provided. An external preparation which comprises the following components (a) and (b); component (a): an ionic drug, component (b): an ionic liquid containing a cation and an anion. By this construction, the ionic liquid functions as a solubilizing agent for the ionic drug and thereby the solubility of the drug in the external preparation increases, so that percutaneous absorption ability of the ionic drug is accelerated.