Methyl 2-methoxy-5-methylisonicotinate | 944838-10-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Methyl 2-methoxy-5-methylisonicotinate
• 英文别名: methyl 2-methoxy-5-methylpyridine-4-carboxylate
• CAS: 944838-10-2
• 化学式: C₉H₁₁NO₃
• 分子量: 181.19
• InChiKey: REHJRGYFWQZKDG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  48.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• HYDANTOIN COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
  申请人：Merck Sharp & Dohme Corp.

  公开号：EP1973900B1

  公开（公告）日：2017-04-05
• Compounds for the treatment of inflammatory disorders
  申请人：Lavey J. Brian

  公开号：US20070265299A1

  公开（公告）日：2007-11-15

  This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPS, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.
• COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
  申请人：Lavey Brian J.

  公开号：US20100120838A1

  公开（公告）日：2010-05-13

  This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.
• US7683088B2
  申请人：——

  公开号：US7683088B2

  公开（公告）日：2010-03-23
• US8178553B2
  申请人：——

  公开号：US8178553B2

  公开（公告）日：2012-05-15