3-苄基腺嘌呤 | 103984-25-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 中文名称: 3-苄基腺嘌呤
• 英文名称: 3-benzyladenine
• 英文别名: 2-benzyl-7(9)H-purin-6-ylamine；US9138393, 3-Benzyladenine；2-benzyl-7H-purin-6-amine
• CAS: 103984-25-4
• 化学式: C₁₂H₁₁N₅
• 分子量: 225.253
• InChiKey: LHPVTMAMEMZFIJ-UHFFFAOYSA-N

物化性质

• 沸点：
  377.3±52.0 °C(Predicted)
• 密度：
  1.44±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  80.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  甲酸 、 2-Benzyl-4,6-diamino-5-nitroso-pyrimidin 在 sodium dithionite 、 formamide 作用下， 生成 3-苄基腺嘌呤
  参考文献：
  名称：

  Synthesis of 2-Aminonicotinamides by Raney Nickel Cleavage of Pyrazolo[3,4-b]-pyridines¹

  摘要：

  DOI：

  10.1021/ja01519a043

文献信息

• [EN] PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST<br/>[FR] COMPOSÉ DE PYRIDINE, COMPOSITION PESTICIDE ET PROCÉDÉ DE LUTTE CONTRE LES NUISIBLES
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2009066786A1

  公开（公告）日：2009-05-28

  A pyridine compound represented by the following general formula (1); the pyridine compound in which R1 is a C1-C3 fluoroalkyl group or a C1-C3 fluoroalkoxy group; the pyridine compound in which R2 is a hydrogen atom; the pyridine compound in which R2 is a group represented by Q1; a pesticidal composition containing the pyridine compound as an active ingredient; and a method of controlling a pest including applying an effective amount of the pyridine compound to the pest or a place where the pest inhabits, are provided.

  以下是通用公式（1）表示的吡啶化合物；其中R1是C1-C3氟烷基或C1-C3氟烷氧基的吡啶化合物；其中R2是氢原子的吡啶化合物；其中R2是由Q1表示的基团的吡啶化合物；包含所述吡啶化合物作为活性成分的杀虫剂组合物；以及一种控制害虫的方法，包括向害虫或害虫栖息地施加有效量的吡啶化合物。
• HETEROARYLAZOLE COMPOUND AND PEST CONTROL AGENT
  申请人：Nippon Soda Co., Ltd.

  公开号：US20210380556A1

  公开（公告）日：2021-12-09

  An object of the present invention is to provide a heteroaryl azole compound that is excellent in pest control activity, particularly, insecticidal activity and/or miticidal activity, is excellent in safety, and may be industrially advantageously synthesized. The compound of the present invention is a compound represented by the formula (I), an N-oxide compound, stereoisomer, tautomer or hydrate thereof or a salt of any of these compounds. In the formula (I), A represents CH or a nitrogen atom; B 1 represents CX 1 or a nitrogen atom; X 1 , X 2 and X 3 each independently represent a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group, a substituted or unsubstituted C2-6 alkenyl group, or the like; R 1 represents a substituted or unsubstituted C1-6 alkylthio group, a substituted or unsubstituted C1-6 alkylsulfinyl group, or the like; R 2 represents a substituted or unsubstituted C1-6 alkyl group; and R represents a substituted or unsubstituted C1-6 alkyl group.

  本发明的一个目的是提供一种在害虫控制活性方面表现出色，特别是在杀虫活性和/或杀螨活性方面表现出色，安全性优秀，并且可以在工业上有利地合成的杂环芳醇类化合物。本发明的化合物是由式（I）表示的化合物，其N-氧化物化合物，立体异构体，互变异构体或其水合物，或这些化合物的任何盐。在式（I）中，A代表CH或氮原子；B1代表CX1或氮原子；X1，X2和X3分别独立地代表氢原子，取代或未取代的C1-6烷基基团，取代或未取代的C2-6烯基基团，或类似物；R1代表取代或未取代的C1-6烷基硫基团，取代或未取代的C1-6烷基亚硫氧基团，或类似物；R2代表取代或未取代的C1-6烷基基团；R代表取代或未取代的C1-6烷基基团。
• (HETERO)ARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT
  申请人：Nippon Soda Co., Ltd.

  公开号：US20210380554A1

  公开（公告）日：2021-12-09

  An object of the present invention is to provide a (hetero)aryl imidazole compound that is excellent in pest control activity, particularly, insecticidal activity and/or acaricidal activity, is excellent in safety, and may be industrially advantageously synthesized. The (hetero)aryl imidazole compound of the present invention is a compound represented by the formula (I) an N-oxide compound, stereoisomer, tautomer or hydrate thereof or a salt of any of these compounds. In the formula (I), B 1 represents a nitrogen atom or CH; X represents a substituted or unsubstituted C3-8 cycloalkyl group; R 1 represents a substituted or unsubstituted C1-6 alkylthio group or a substituted or unsubstituted C1-6 alkylsulfonyl group; R 2 represents a substituted or unsubstituted C1-6 alkyl group; and R represents a substituted or unsubstituted C2-6 alkenyl group.

  本发明的一个目的是提供一种在害虫控制活性方面表现出色，特别是在杀虫活性和/或杀螨活性方面表现出色，安全性优秀，并且可以在工业上有利地合成的（杂）芳基咪唑化合物。本发明的（杂）芳基咪唑化合物是由以下式（I）表示的化合物 一种N-氧化物化合物，立体异构体，互变异构体或其水合物，或这些化合物的任何盐。在式（I）中，B 1 代表氮原子或CH；X代表取代或未取代的C3-8环烷基基团；R 1 代表取代或未取代的C1-6烷硫基团或取代或未取代的C1-6烷基磺酰基团；R 2 代表取代或未取代的C1-6烷基基团；而R代表取代或未取代的C2-6烯基基团。
• Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)
  申请人：CHEN Han-Min

  公开号：US20140303112A1

  公开（公告）日：2014-10-09

  The present invention relates to a method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) and the use of the compounds in the prevention or treatment of disease, including pre-diabetes, type 2 diabetes, syndrome X, metabolic syndrome and obesity.

  本发明涉及一种治疗疾病或病情的方法，该疾病或病情容易通过AMPK激活剂和公式化合物得到改善，这些化合物有助于激活AMP激活蛋白激酶（AMPK），并将这些化合物用于预防或治疗疾病，包括糖尿病前期、2型糖尿病、X综合症、代谢综合征和肥胖症。
• DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM
  申请人：Nippon Soda Co., Ltd.

  公开号：US20190185459A1

  公开（公告）日：2019-06-20

  A compound represented by Formula (I), or a salt thereof: wherein, R 1 represents an unsubstituted or substituted C1-6 alkylthio group, or the like; A 1 represents a nitrogen atom or CH; A 2 represents a nitrogen atom or CR 2 ; R 2 and R 3 each independently represents a hydrogen atom, an unsubstituted or substituted C6-10 aryl group, an unsubstituted or substituted 3- to 6-membered heterocyclyl group, or the like; B 1 and B 2 each independently represents a nitrogen atom or CR 5 , with the proviso that B 1 and B 2 do not represent CR 5 at the same time, wherein R 5 represents a hydrogen atom, an unsubstituted or substituted C1-6 alkyl group, or the like; R 4 represents an unsubstituted or substituted C1-6 alkyl group, or the like, and R 4 binds to any one of nitrogen atoms forming an imidazole ring or a triazole ring; and Ar represents an unsubstituted or substituted C6-10 aryl group or the like.

  通过公式（I）表示的化合物，或其盐：其中，R1代表未取代或取代的C1-6烷基硫基团等；A1代表氮原子或CH；A2代表氮原子或CR2；R2和R3各自独立地代表氢原子、未取代或取代的C6-10芳基团、未取代或取代的3-至6-成员杂环基团等；B1和B2各自独立地代表氮原子或CR5，但须注意B1和B2不同时代表CR5，其中R5代表氢原子、未取代或取代的C1-6烷基团等；R4代表未取代或取代的C1-6烷基团等，且R4与形成咪唑环或三唑环的任一氮原子结合；Ar代表未取代或取代的C6-10芳基团等。