Methylidene-diphenyl-pyridin-2-yl-lambda5-phosphane | 76795-77-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Methylidene-diphenyl-pyridin-2-yl-lambda5-phosphane
• 英文别名: methylidene-diphenyl-pyridin-2-yl-λ5-phosphane
• CAS: 76795-77-2
• 化学式: C₁₈H₁₆NP
• 分子量: 277.305
• InChiKey: ZVZSFXNMIQHBKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  二苯基-2-吡啶膦 以 苯 为溶剂， 反应 1.0h， 生成 Methylidene-diphenyl-pyridin-2-yl-lambda5-phosphane
  参考文献：
  名称：

  Schmidbaur, Hubert; Inoguchi, Yoshio, Zeitschrift fur Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980, vol. 35, # 11, p. 1329 - 1334

  摘要：

  DOI：

文献信息

• SCHMIDBAUER H.; INOGUCHI YOSHIO, Z. NATURFORSCH., 1980, B 35, NO 11,1329-1334
  作者：SCHMIDBAUER H.、 INOGUCHI YOSHIO

  DOI：——

  日期：——
• Gold (I)-Phosphine Compounds as Anti-Bacterial Agents
  申请人：Auspherix Limited

  公开号：US20170204123A1

  公开（公告）日：2017-07-20

  A compound of formula (I) for use in the prevention or treatment of a bacterial infection wherein R P1 is either methyl, ethyl, isopropyl, cyclohexyl or phenyl; R P2 is selected from methyl, ethyl, isopropyl, cyclohexyl and phenyl; R P3 is either ethyl, isopropyl, cyclohexyl, phenyl or pyridyl; A is either S or Se; R A is selected from wherein each of Y 1 , Y 2 , Y 3 , Y 4 and Y 9 is independently selected from CH or N, wherein at least three of Y 1 , Y 2 , Y 3 , Y 4 and Y 9 are CH; V is selected from O, CH—OR O1 , N—CO 2 —R C2 or N—R N2 ; one of V, Y 6 , Y 7 and Y 8 is selected from CH and N, and the others are CH; X is selected from NH, S or O; R C1 is selected from O—R O2 or NHR N1 ; R O1 is selected from H and C 1-3 unbranched alkyl; R O2 is C 1-3 unbranched alkyl; R N1 is selected from H and C 1-3 unbranched alkyl; R N2 is C 1-3 unbranched alkyl; R C2 is either C 1-3 unbranched alkyl or C 3-4 branched alkyl; R C3 is selected from C 1-3 unbranched alkyl and C 2 H 4 CO 2 H; R C4 is either H or Me; R C5 is either H or Me; R C6 represents one or two optional methyl substituents; and n is an integer from 2 to 8.