N-Methylhexahydrocyclopenta[c]pyrrol-2(1H)-amine | 54528-01-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: N-Methylhexahydrocyclopenta[c]pyrrol-2(1H)-amine
• 英文别名: N-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-amine
• CAS: 54528-01-7
• 化学式: C₈H₁₆N₂
• 分子量: 140.23
• InChiKey: WIRZQCKLOALVJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• THERAPEUTIC AGENT FOR CEREBRAL INFARCTION
  申请人：Nakao Akira

  公开号：US20120196824A1

  公开（公告）日：2012-08-02

  The invention provides a therapeutic drug for ischemic stroke. The therapeutic drug has the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof, as an active ingredient.

  这项发明提供了一种用于缺血性中风的治疗药物。该治疗药物具有如下式（I）的化学式，其中每个符号如本文所定义，或其药理学上可接受的盐，或其溶剂化物，作为活性成分。
• OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
  申请人：BARTH Francis

  公开号：US20070043060A1

  公开（公告）日：2007-02-22

  This invention relates to compounds of formula (I): Wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are as described herein. The invention further relates to a method for prevention and therapeutic use thereof.

  本发明涉及式(I)化合物：其中R1、R2、R3、R4、R5、R6、R7和R8如本文所述。本发明还涉及其预防和治疗用途的方法。
• 4-CYANOPYRAZOLE-3-CARBOXAMIDE DERIVATIVES, PREPARATION AND APPLICATION THEREOF
  申请人：BARTH Francis

  公开号：US20070293541A1

  公开（公告）日：2007-12-20

  The invention relates to 4-cyanopyrazole-3-carboxamide derivatives of formula (I): in which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 are as described herein. Also disclosed and claimed are the method of preparation and therapeutic application of compound of formula (I).

  本发明涉及式（I）的4-氰基吡唑-3-羧酰胺衍生物： 其中R1、R2、R3、R4、R5、R6、R7、R8如本文所述。本发明还揭示和声明了式（I）化合物的制备方法和治疗应用。
• HOMOCYSTEINE SYNTHASE INHIBITOR
  申请人：Nakao Akira

  公开号：US20110034440A1

  公开（公告）日：2011-02-10

  The invention provides a homocysteine synthase inhibitor useful for the prophylaxis or treatment of diseases involving homocysteine synthase. The homocysteine synthase inhibitor is a compound of the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof.

  本发明提供了一种同型半胱氨酸合酶抑制剂，可用于预防或治疗涉及同型半胱氨酸合酶的疾病。该同型半胱氨酸合酶抑制剂是公式(I)的化合物，其中每个符号如本文所定义，或其药理学上可接受的盐，或其溶剂化物。
• US7282516B2
  申请人：——

  公开号：US7282516B2

  公开（公告）日：2007-10-16