3-methyl-3-(pyridin-2-yl)butan-2-one | 62415-78-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-methyl-3-(pyridin-2-yl)butan-2-one
• 英文别名: 3-methyl-3-pyridin-2-ylbutan-2-one
• CAS: 62415-78-5
• 化学式: C₁₀H₁₃NO
• 分子量: 163.219
• InChiKey: VTOMHEDQTZTKCC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  30
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Organic Compounds
  申请人：Herold Peter

  公开号：US20080058320A1

  公开（公告）日：2008-03-06

  The invention relates to novel amino alcohols of the general formula (I) where X, R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are each as defined in detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors.

  本发明涉及一种新型的氨基醇，其通式为(I)，其中X，R1，R2，R3，R4，R5和R6分别如详细描述中所定义，以及其制备方法和这些化合物作为药物的用途，特别是作为肾素抑制剂。
• Diaminoalcohols as therapeutic compounds
  申请人：Herold Peter

  公开号：US20070066582A1

  公开（公告）日：2007-03-22

  Use of compounds of the general formula (I) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and X have the definitions elucidated in more detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibitors.

  使用一般公式(I)，其中R1，R2，R3，R4，R5，R6和X的定义在描述中更详细地阐述，作为β-秘鲁酶、天门冬氨酸蛋白酶D、质膜酶II和/或HIV蛋白酶抑制剂的复合物。
• Method for preparing poly(carbonate-etherimide) compound
  申请人：PTT Global Chemical Public Company Limited

  公开号：US10759904B2

  公开（公告）日：2020-09-01

  The present invention relates to a method for preparing poly(carbonate-etherimide) compound comprising polycarbonate segment as shown in the structure (A) and polyetherimide segment as shown in the structure (B). Said method does not contain a highly toxic phosgene in its operation, can be performed easily, and can be operated at not high temperature. wherein R1 represents aromatic with 6 to 30 carbon atoms or, optionally said aromatic is bonded with heteroatom; R2 represents aromatic with 6 to 30 carbon atoms or, optionally said aromatic is bonded with heteroatom; m is an integer from 1 to 15; and n is an integer from 1 to 10.

  本发明涉及一种制备聚(碳酸酯-乙醚酰亚胺)化合物的方法，该化合物由结构(A)所示的聚碳酸酯段和结构(B)所示的聚醚酰亚胺段组成。本发明涉及一种制备聚碳酸酯-乙烯酰亚胺化合物的方法，该化合物包括结构（A）所示的聚碳酸酯段和结构（B）所示的聚醚酰亚胺段，该方法在操作过程中不含有剧毒的光气，操作简便，可在不高的温度下进行。
• A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND
  申请人：PTT Global Chemical Public Company Limited

  公开号：EP3405453A2

  公开（公告）日：2018-11-28
• METHOD FOR PREPARING POLY(CARBONATE-ETHERIMIDE) COMPOUND
  申请人：PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED

  公开号：US20190202980A1

  公开（公告）日：2019-07-04

  The present invention relates to a method for preparing poly(carbonate-etherimide) compound comprising polycarbonate segment as shown in the structure (A) and polyetherimide segment as shown in the structure (B). Said method does not contain a highly toxic phosgene in its operation, can be performed easily, and can be operated at not high temperature. wherein R 1 represents aromatic with 6 to 30 carbon atoms or, optionally said aromatic is bonded with heteroatom; R 2 represents aromatic with 6 to 30 carbon atoms or, optionally said aromatic is bonded with heteroatom; m is an integer from 1 to 15; and n is an integer from 1 to 10.