N-(2-aminophenyl)-4-((5,6-dimethoxy-4-(3,5-dimethylphenyl)-1-oxoisoindolon-2-yl)methyl)benzamide | 1255950-63-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2-aminophenyl)-4-((5,6-dimethoxy-4-(3,5-dimethylphenyl)-1-oxoisoindolon-2-yl)methyl)benzamide
• 英文别名: N-(2-aminophenyl)-4-((5,6-dimethoxy-4-(3,5-dimethylphenyl)-1-oxoisoindolin-2-yl)methyl)benzamide；N-(2-aminophenyl)-4-[[7-(3,5-dimethylphenyl)-5,6-dimethoxy-3-oxo-1H-isoindol-2-yl]methyl]benzamide
• CAS: 1255950-63-0
• 化学式: C₃₂H₃₁N₃O₄
• 分子量: 521.616
• InChiKey: GTNXKRSMQGLOQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  39
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  93.9
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• ISOINDOLINONE DERIVATIVES, PREPARATION METHOD THEREOF AND A PHARMACEUTICAL COMPOSITION COMPRISING SAME
  申请人：Heo Jung Nyoung

  公开号：US20120065396A1

  公开（公告）日：2012-03-15

  The present invention relates to an amide compound or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition comprising the same. The inventive amide compound facilitates bone formation and inhibits bone loss, and is therefore useful for preventing and treating bone disorders such as osteoporosis, osteodystrophy, bone fracture, periodontal disease, Paget's disease, bone metastasis, and rheumatoid arthritis.

  本发明涉及一种酰胺化合物或其药学上可接受的盐，其制备方法以及包含它的制药组合物。本发明的酰胺化合物促进骨形成并抑制骨丢失，因此可用于预防和治疗骨疾病，如骨质疏松症、骨发育不良、骨折、牙周疾病、Paget病、骨转移和类风湿性关节炎。
• Fiber-reinforced rocket motor insulation
  申请人：——

  公开号：US20020189233A1

  公开（公告）日：2002-12-19

  Insulation for a rocket motor is provided, as is a method for insulating a rocket motor. The insulation includes a cured elastomer and vapor grown carbon fibers dispersed in the cured elastomer. The cured elastomer is preferably formed from a precursor composition comprising an EPDM terpolymer. Generally, the vapor grown carbon fibers have an internal graphitized tube surrounded by a sheath of vapor deposited amorphous carbon.

  提供了火箭发动机的隔热材料和火箭发动机的隔热方法。隔热材料包括固化弹性体和分散在固化弹性体中的气相生长碳纤维。固化弹性体最好由包含三元乙丙橡胶三元共聚物的前体组合物形成。一般来说，气相生长碳纤维有一个内部石墨化管，周围有一层气相沉积无定形碳鞘。
• FIBER-REINFORCED ROCKET MOTOR INSULATION
  申请人：Alliant Techsystems Inc.

  公开号：EP1373386A2

  公开（公告）日：2004-01-02
• AMIDE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
  申请人：Korea Research Institute Of Chemical Technology

  公开号：EP2429987A2

  公开（公告）日：2012-03-21
• INSULATIVE COMPOSITIONS, ARTICLE INCORPORATING THE SAME AND METHODS OF FORMING THE SAME
  申请人：Gajiwala Himansu M.

  公开号：US20120065294A1

  公开（公告）日：2012-03-15

  Precursors, insulative compositions, an article including the insulative compositions and a method for making the insulative compositions are disclosed. The insulative compositions are formed from a precursor composition that includes a nitride butadiene rubber, a nanoclay and a cure package including a sulfur-based curing agent. The insulative compositions may have a substantially reduced weight and compressive modulus in comparison to conventional insulative rubbers. Thus, the insulative compositions may provide improved ballistic properties in addition to reduced density and thickness. Precursor compositions for forming the insulative composition may have good flow characteristics. The insulative compositions may be used in a variety of applications, such as personnel body armor, ground vehicle armor and aircraft armor systems.