1-[2-(2-hydroxy-ethoxy)-ethyl]-pyrrolidin-2-one | 2176-49-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 1-[2-(2-hydroxy-ethoxy)-ethyl]-pyrrolidin-2-one
• 英文别名: 1-[2-(2-Hydroxyethoxy)ethyl]pyrrolidin-2-one
• CAS: 2176-49-0
• 化学式: C₈H₁₅NO₃
• 分子量: 173.212
• InChiKey: VOVPPAZBOSDQBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• CATALYTIC PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS
  申请人：Bergmann Hermann

  公开号：US20100010236A1

  公开（公告）日：2010-01-14

  A process for preparing (meth)acrylic esters (F) of N-hydroxyalkylated lactams, in which cyclic N-hydroxyalkylated lactams (L) in which R 1 is C 1 -C 5 -alkylene, or C 2 -C 20 -alkylene interrupted by one or more oxygen and/or sulfur atoms and/or one or more substituted or unsubstituted imino groups and/or by one or more cycloalkyl, —(CO)—, —O(CO)O—, —(NH)(CO)O—, —O(CO)(NH)—, —O(CO)— or —(CO)O— groups, where the radicals mentioned may each be substituted by aryl, alkyl, aryloxy, alkyloxy, heteroatoms and/or heterocycles, with the proviso that R 1 must not have any atom other than a carbon atom directly adjacent to the lactam carbonyl group, R 2 is C 1 -C 20 -alkylene, C 5 -C 12 -cycloalkylene, C 6 -C 12 -arylene, or C 2 -C 20 -alkylene interrupted by one or more oxygen and/or sulfur atoms and/or one or more substituted or unsubstituted imino groups and/or by one or more cycloalkyl, —(CO)—, —O(CO)O—, —(NH)(CO)O—, —O(CO)(NH)—, —O(CO)— or —(CO)O— groups, where the radicals mentioned may each be substituted by aryl, alkyl, aryloxy, alkyloxy, heteroatoms and/or heterocycles, or R 2 —OH is a group of the formula —[X i ] k —H, k is from 1 to 50 and X i , for each i=1 to k, may each independently be selected from the group of —CH 2 —CH 2 —O—, —CH 2 —CH 2 —N(H)—, —CH 2 —CH 2 —CH 2 —N(H)—, —CH 2 —CH(NH 2 )—, —CH 2 —CH(NHCHO)—, —CH 2 —CH(CH 3 )—O—, —CH(CH 3 )—CH 2 —O—, —CH 2 —C(CH 3 ) 2 —O—, —C(CH 3 ) 2 —CH 2 —O—, —CH 2 —CH 2 —CH 2 —O—, —CH 2 —CH 2 —CH 2 —CH 2 —O—, —CH 2 —CHVin—O—, —CHVin—CH 2 —O—, —CH 2 —CHPh—O— and —CHPh—CH 2 —O—, in which Ph is phenyl and Vin is vinyl, in the presence of at least one metal salt of C 1 -C 10 -alkoxides (A), is esterified with (meth)acrylic acid (S) or transesterified with at least one (meth)acrylic ester (D), in which the metal salt of C 1 -C 10 -alkoxides (A) used as a catalyst is added in the absence of solvents and completely at the start of the reaction.

  一种制备N-羟基烷基化内酰胺的（甲基）丙烯酸酯（F）的方法，其中，环状的N-羟基烷基化内酰胺（L）中，R1为C1-C5烷基，或C2-C20烷基，其中间断有一个或多个氧和/或硫原子和/或一个或多个取代或未取代的亚胺基团和/或一个或多个环烷基，—（CO）—，—O（CO）O—，—（NH）（CO）O—，—O（CO）（NH）—，—O（CO）—或—（CO）O—基团，所述基团中每个都可以被芳香基，烷基，芳氧基，烷氧基，杂原子和/或杂环取代，但R1不能在内酰胺羰基团直接相邻的位置上有任何原子；R2为C1-C20烷基，C5-C12环烷基，C6-C12芳基烷基，或C2-C20烷基，其中间断有一个或多个氧和/或硫原子和/或一个或多个取代或未取代的亚胺基团和/或一个或多个环烷基，—（CO）—，—O（CO）O—，—（NH）（CO）O—，—O（CO）（NH）—，—O（CO）—或—（CO）O—基团，所述基团中每个都可以被芳香基，烷基，芳氧基，烷氧基，杂原子和/或杂环取代，或R2—OH是一个公式为—[Xi]k—H的基团，其中k为1至50，对于每个i=1至k，Xi可以各自独立地从—CH2— —O—，— — —N（H）—，— — — —N（H）—，— —CH（NH2）—，— —CH（NHCHO）—，— —CH（CH3）—O—，—CH（ ）— —O—，— —C（ ）2—O—，—C（ ）2— —O—，— — — —O—，— — — — —O—，— —CHVin—O—，—CHVin— —O—，— —CHPh—O—和—CHPh— —O—中的一组中选择，其中Ph为苯基，Vin为乙烯基，在至少一种C1-C10烷氧基金属盐（A）的存在下，与（甲基）丙烯酸（S）酯化或与至少一种（甲基）丙烯酸酯（D）交酯化，所述用作催化剂的C1-C10烷氧基金属盐（A）在反应开始时在无溶剂的情况下完全添加。
• CATALYTIC PROCESS FOR PREPARING (METH)ACRYLATES FROM N-HYDROXYALKYLATED LACTAMS
  申请人：Hofer Frank

  公开号：US20070123673A1

  公开（公告）日：2007-05-31

  Process for catalytically preparing (meth)acrylates of N-hydroxyalkylated lactams, and use thereof.

  催化制备N-羟基烷基内酰胺(meth)丙烯酸酯的过程及其应用。
• FUEL COMPOSITIONS
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0692011B1

  公开（公告）日：1996-11-06
• HYDROGEN KATALYSIERTES VERFAHREN ZUR HERSTELLUNG VON (METH)ACRYLATEN VON N-HYDROXYALKYLIERTEN LACTAMEN
  申请人：BASF SE

  公开号：EP1945602B1

  公开（公告）日：2012-08-01
• KATALYTISCHES VERFAHREN ZUR HERSTELLUNG VON (METH)ACRYLSÄUREESTERN VON N-HYDROXYALKYLIERTEN LACTAMEN
  申请人：BASF SE

  公开号：EP2121595A1

  公开（公告）日：2009-11-25