Benzyl 4-((3-chlorophenyl)amino)-4-cyanopiperidine-1-carboxylate | 1219969-95-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl 4-((3-chlorophenyl)amino)-4-cyanopiperidine-1-carboxylate
• 英文别名: benzyl 4-(3-chloroanilino)-4-cyanopiperidine-1-carboxylate
• CAS: 1219969-95-5
• 化学式: C₂₀H₂₀ClN₃O₂
• 分子量: 369.8
• InChiKey: POLPZRHGWYMMSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  65.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Melanocortin Receptor-Specific Spiro-Piperidine Compounds
  申请人：Shi Yi-Qun

  公开号：US20110178080A1

  公开（公告）日：2011-07-21

  Melanocortin receptor-specific compounds of formula I below: wherein the variables are as defined in the specification, and enantiomers, diastereomers and pharmaceutically acceptable salts thereof. Compounds disclosed herein bind to one or more melanocortin receptors and may be an agonist, a partial agonist, an antagonist, an inverse agonist or an antagonist of an inverse agonist as to one or more melanocortin receptors, and may be employed for treatment of one or more melanocortin receptor-associated conditions or disorders.
• US8263608B2
  申请人：——

  公开号：US8263608B2

  公开（公告）日：2012-09-11
• [EN] MELANOCORTIN RECEPTOR-SPECIFIC SPIRO-PIPERIDINE COMPOUNDS<br/>[FR] COMPOSÉS DE SPIROPIPÉRIDINE SPÉCIFIQUES DU RÉCEPTEUR DE LA MÉLANOCORTINE
  申请人：PALATIN TECHNOLOGIES INC

  公开号：WO2010037081A1

  公开（公告）日：2010-04-01

  Melanocortin receptor-specific compounds of formula (I) below, wherein the variables are as defined in the specification, and enantiomers, diastereomers and pharmaceutically acceptable salts thereof. Compounds disclosed herein bind to one or more melanocortin receptors and may be an agonist, a partial agonist, an antagonist, an inverse agonist or an antagonist of an inverse agonist as to one or more melanocortin receptors, and may be employed for treatment of one or more melanocortin receptor-associated conditions or disorders.