3-(2-Carboxy-phenyl)-isonicotinsaeure | 96460-89-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-(2-Carboxy-phenyl)-isonicotinsaeure
• 英文别名: 3-(2-carboxy-phenyl)-isonicotinic acid；3-o-Carboxyphenylisonicotinic acid；3-(2-carboxyphenyl)pyridine-4-carboxylic acid
• CAS: 96460-89-8
• 化学式: C₁₃H₉NO₄
• 分子量: 243.219
• InChiKey: SVPSJXFWMRPLOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  87.5
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Environment-responsive hyaluronic acid nanoparticles
  申请人：Industry-University Cooperation Foundation Hanyang University

  公开号：US10555965B2

  公开（公告）日：2020-02-11

  The present invention relates to glucose-responsive hyaluronic acid nanoparticles having boronic acid compounds chemically bonded thereto, and a composition including the same. When the nanoparticles according to the present invention are used, cancer may be diagnosed and treated using a cancer cell-specific biological mechanism, without the use of existing contrast agents and anticancer agents which have the problem of toxicity.

  本发明涉及葡萄糖响应型透明质酸纳米粒子（其上化学键合有硼酸化合物）以及包括其在内的组合物。使用本发明的纳米粒子时，可利用癌细胞特异性生物机制诊断和治疗癌症，而无需使用现有的具有毒性问题的造影剂和抗癌剂。
• ENVIRONMENT-RESPONSIVE HYALURONIC ACID NANOPARTICLES
  申请人：Industry-University Cooperation Foundation Hanyang University

  公开号：US20180369276A1

  公开（公告）日：2018-12-27

  The present invention relates to glucose-responsive hyaluronic acid nanoparticles having boronic acid compounds chemically bonded thereto, and a composition including the same. When the nanoparticles according to the present invention are used, cancer may be diagnosed and treated using a cancer cell-specific biological mechanism, without the use of existing contrast agents and anticancer agents which have the problem of toxicity.