Tetrahydrooxazin | 53544-32-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: Tetrahydrooxazin
• 英文别名: 2,6-dimethyl-[1,2]oxazinane；2,6-Dimethyloxazinane
• CAS: 53544-32-4
• 化学式: C₆H₁₃NO
• 分子量: 115.175
• InChiKey: XYACESPRVSKQCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] NOVEL DOSAGE FORM<br/>[FR] NOUVELLE FORME PHARMACEUTIQUE
  申请人：BIOTICA TECH LTD

  公开号：WO2013061052A1

  公开（公告）日：2013-05-02

  There is provided inter alia apharmaceutical dosage form fororal administration comprising a sanglifehrin as active ingredient in which the sanglifehrin active ingredient is protected from acid degradation in the stomach environment following oral administration.

  提供了一种口服药物剂型，包括桑格利非林作为活性成分，其中桑格利非林活性成分在口服后胃环境中受到酸性降解的保护。
• Novel Dosage Form
  申请人：NeuroVive Pharmaceutical AB

  公开号：US20140234414A1

  公开（公告）日：2014-08-21

  There is provided inter alia a pharmaceutical dosage form for oral administration comprising a sanglifehrin as active ingredient in which the sanglifehrin active ingredient is protected from acid degradation in the stomach environment following oral administration.

  提供了一种用于口服的药物剂型，包括桑格利非林作为活性成分，其中桑格利非林活性成分在口服后受到胃酸降解的保护。
• Macrocyclic Compounds and Methods for Their Production
  申请人：Moss Steven James

  公开号：US20140038885A1

  公开（公告）日：2014-02-06

  There is provided inter alia compounds of formula (I): for use in treatment of viral infection or as an immunosuppressant.

  提供了公式（I）的化合物，可用于治疗病毒感染或作为免疫抑制剂。
• Heterocyclic diones as pesticides and plant growth regulators
  申请人：SANDOZ AG

  公开号：EP0394889A2

  公开（公告）日：1990-10-31

  Compounds of the general formula I A - - B      I wherein A represents the group (i) in which any free hydrogen may be replaced by an agriculturally acceptable substituent; and B represents an optionally substituted aryl or heteroaryl group are disclosed, as well as methods of producing such compounds, intermediates therefore, and their use as herbicides and acaricides.

  通式 I 的化合物 A - - B I 其中 A 代表基团(i) 其中任何游离氢均可被农业上可接受的取代基取代；B 代表任选取代的芳基或杂芳基。
• SANGLIFEHRIN BASED COMPOUNDS
  申请人：Neurovive Pharmaceutical AB

  公开号：EP2533784B1

  公开（公告）日：2015-04-22