3,6,9,12-Tetraoxatridecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester | 1251908-75-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 3,6,9,12-Tetraoxatridecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
• 英文别名: (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]acetate
• CAS: 1251908-75-4
• 化学式: C₁₃H₂₁NO₈
• 分子量: 319.31
• InChiKey: GZMGHDVOWSDCPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  101
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• Oligomer-Protein Tyrosine Kinase Inhibitor Conjugates
  申请人：Riggs-Sauthier Jennifer

  公开号：US20120071492A1

  公开（公告）日：2012-03-22

  The invention relates to (among other things) oligomer-PTK inhibitor conjugates and related compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over PTK inhibitor compounds lacking a water soluble, non peptidic oligomer.

  本发明涉及寡聚体-PTK抑制剂偶联物和相关化合物（除其他事项外）。本发明中的化合物在通过多种给药途径之一给予时，表现出优于缺乏水溶性非肽寡聚体的PTK抑制剂化合物的优点。
• Surface Modification of Polyamide Reverse Osmosis Membranes
  申请人：Sarkar Abhijit

  公开号：US20120024789A1

  公开（公告）日：2012-02-02

  The present invention relates to surface modification of reverse osmosis membranes to introduce antifouling properties without compromising the separation properties of the original membranes. This approach utilizes: providing a coated membrane surface having enhanced hydrophilic characteristics that prevents the biofoulants from settling; have a surface that consists of hydrophilic brushes that unsettle any biofoulants that get through; and having antimicrobial ions present in the membrane coatings and able to remove or minimize any remaining biofoulants without leaching into the permeate. These coatings are made using dendritic polymers such as hyperbranched polymers or dendrimers.
• US8505743B2
  申请人：——

  公开号：US8505743B2

  公开（公告）日：2013-08-13
• US8816077B2
  申请人：——

  公开号：US8816077B2

  公开（公告）日：2014-08-26
• US9084828B2
  申请人：——

  公开号：US9084828B2

  公开（公告）日：2015-07-21