6-Ethyl-6-phenyl-azepinon-(2) | 92499-39-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 英文名称: 6-Ethyl-6-phenyl-azepinon-(2)
• 英文别名: 6-Ethyl-6-phenylazepan-2-one
• CAS: 92499-39-3
• 化学式: C₁₄H₁₉NO
• 分子量: 217.311
• InChiKey: YZHYSMHJTPVGGF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• 3-ETHYL-3-PHENYLAZEPANE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
  申请人：LABORATORIOS DEL DR. ESTEVE S.A.

  公开号：US20190031615A1

  公开（公告）日：2019-01-31

  The present invention relates to 3-ethyl-3-phenylazepane derivatives having dual pharmacological activity towards both the sigma (σ) receptor and the μ-opioid receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.