11,12-Dihydro-5H,10H-12,16b-ethano-5a,11-methano-10-(dicarbmethoxymethyl)dibenzo<3,4:8,9>cyclonona<1,2-b>naphtho<1,2-e>pyran-20,22-dione | 135106-96-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: 11,12-Dihydro-5H,10H-12,16b-ethano-5a,11-methano-10-(dicarbmethoxymethyl)dibenzo<3,4:8,9>cyclonona<1,2-b>naphtho<1,2-e>pyran-20,22-dione
• CAS: 135106-96-6
• 化学式: C₃₆H₂₈O₇
• 分子量: 572.614
• InChiKey: GVYLLCYFXMVAEK-HFOBBWOWSA-N

反应信息

• 作为产物：
  描述：

  cis-bispiro--pyran-3',1"-naphthalene>-2(1H),2"(1"H)-dione 、 丙二酸二甲酯 在 potassium tert-butylate 作用下， 生成 11,12-Dihydro-5H,10H-12,16b-ethano-5a,11-methano-10-(dicarbmethoxymethyl)dibenzo<3,4:8,9>cyclonona<1,2-b>naphtho<1,2-e>pyran-20,22-dione
  参考文献：
  名称：

  Tandem Michael reaction. Synthesis of bridged diketones

  摘要：

  Addition of NaOMe, NaOEt, or NaOPr(i) to dispironaphthalenone 1 resulted in the formation of diketones 4a-c and 5a-c. The structure assigned to 4a was confirmed by conversion to the known hemiacetal 3. Similar addition of carbon nucleophiles like diethyl malonate, dimethyl malonate, methyl cyanoacetate, and ethyl cyanoacetate afforded diketones 4d-g. Formation of these compounds has been rationalized.

  DOI：

  10.1021/jo00019a018