2,5-bis(5-bromo-2-hydroxyphenyl)-1,3,4-oxadiazole | 2491-97-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2,5-bis(5-bromo-2-hydroxyphenyl)-1,3,4-oxadiazole
• 英文别名: 6,6'-(1,3,4-Oxadiazolidine-2,5-diylidene)bis(4-bromocyclohexa-2,4-dien-1-one)；4-bromo-2-[5-(5-bromo-2-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]phenol
• CAS: 2491-97-6
• 化学式: C₁₄H₈Br₂N₂O₃
• 分子量: 412.037
• InChiKey: LOIOFWBMNVCWJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  79.4
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  5-溴水杨酸 在 PPA 、 盐酸氨基脲 作用下， 反应 3.0h， 以51%的产率得到2,5-bis(5-bromo-2-hydroxyphenyl)-1,3,4-oxadiazole
  参考文献：
  名称：

  Bis(2-hydroxyphenyl)-1,3,4-oxadiazole Derivative for Anion Sensing and Fluorescent Patterning

  摘要：

  We have attempted to synthesize an oxadiazole compound which has ability of anion sensing and of fluorescent pattern construction. Organic soluble oxadiazole molecule with adjacent hydroxyphenyl groups for excited- state intramolecular proton transfer ( ESIPT) was synthesized. Significant UV- vis absorption and fluorescence changes were observed upon addition of F-. UV- irradiation on the poly ( methyl methacrylate) ( PMMA) film doped with oxadiazole compound in the presence of photoacid generator ( PAG) induced novel fluorescence quenching- induced patterning.

  DOI：

  10.1080/15421400601028054