3,5-dimethyloxy-4-ethyloxycarbonyldimethylmethyloxybenzaldehyde | 923978-96-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,5-dimethyloxy-4-ethyloxycarbonyldimethylmethyloxybenzaldehyde
• 英文别名: Ethyl 2-(4-formyl-2,6-dimethoxyphenoxy)-2-methylpropanoate
• CAS: 923978-96-5
• 化学式: C₁₅H₂₀O₆
• 分子量: 296.32
• InChiKey: DWASQDYQGBCXQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients
  申请人：Delhomel Francois Jean

  公开号：US20070032543A1

  公开（公告）日：2007-02-08

  The invention concerns novel substituted 1,3-diphenylprop-2-en-1-one derivatives and combinations of said derivatives with other therapeutically active ingredients. The invention also concerns compositions comprising said derivatives or said combinations and uses thereof, for the treatment of cerebrovascular diseases, pathology related to inflammation, neurodegeneration, deregulations of lipid and/or glucose metabolism, cell proliferation and/or differentiation and/or skin or central nervous system ageing.

  本发明涉及新的取代的1,3-二苯基丙烯酮衍生物以及该衍生物与其他治疗活性成分的组合物。本发明还涉及包含该衍生物或该组合物的组合物，以及用于治疗脑血管疾病、与炎症相关的病理学、神经退行性、脂质和/或葡萄糖代谢紊乱、细胞增殖和/或分化和/或皮肤或中枢神经系统衰老的用途。
• COMPOSITION BASED ON SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES, PREPARATION AND USES THEREOF
  申请人：Najib Jamila

  公开号：US20100120909A1

  公开（公告）日：2010-05-13

  The invention concerns compositions comprising substituted 1,3-diphenylprop-2-en-1-one derivatives designed for therapeutic use. The inventive compositions are useful in particular for preventing or treating cardiovascular diseases, syndrome X, Ia restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative, dermatological diseases and disorders related to oxidative stress, for preventing or treating the effects of ageing in general and for example skin ageing, in particular in the field of cosmetics (occurrence of wrinkles and the like).

  该发明涉及一种用于治疗的取代的1,3-二苯基丙烯酮衍生物组合物。该发明的组合物特别适用于预防或治疗心血管疾病、X综合征、Ia再狭窄、糖尿病、肥胖症、高血压、炎症性疾病、癌症或肿瘤（良性或恶性肿瘤）、神经退行性疾病、皮肤病以及与氧化应激有关的疾病和紊乱，用于预防或治疗衰老的影响，例如皮肤衰老，在化妆品领域（皱纹等的出现）。
• SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES, PREPARATION AND USES THEREOF
  申请人：NAJIB Jamila

  公开号：US20110190515A1

  公开（公告）日：2011-08-04

  The invention concerns novel substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions comprising same, their therapeutic uses, in particular for treating cerebral ischemia. The invention also concerns a method for preparing said derivatives.

  本发明涉及新的取代的1,3-二苯基丙烯酮衍生物，包括这些衍生物的药物组合物，它们的治疗用途，特别是用于治疗脑缺血。本发明还涉及一种制备上述衍生物的方法。
• COMPOSITION A BASE DE DERIVES DE 1,3-DIPHENYLPROP-2-EN-1-ONE SUBSTITUES, PREPARATIONS ET UTILISATIONS
  申请人：Genfit

  公开号：EP1519908B1

  公开（公告）日：2007-06-13
• DERIVES DE 1,3-DIPHENYLPROP-2-EN-1-ONE SUBSTITUES, PREPARATIONS ET UTILISATIONS
  申请人：Genfit

  公开号：EP1525177B1

  公开（公告）日：2007-06-27