(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)-2-(4-methoxybenzylmethyl)-1-methoxypyrrolidine | 1438263-53-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)-2-(4-methoxybenzylmethyl)-1-methoxypyrrolidine
• CAS: 1438263-53-6
• 化学式: C₃₆H₄₁NO₆
• 分子量: 583.725
• InChiKey: GMGVAVVRNWCHBE-MGXDLYCJSA-N

反应信息

• 作为产物：
  描述：

  在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 反应 2.0h， 生成 (2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)-2-(4-methoxybenzylmethyl)-1-methoxypyrrolidine 、 (2S,3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)-2-(4-methoxybenzylmethyl)-1-methoxypyrrolidine
  参考文献：
  名称：

  Stereoselective synthesis of (2S,3S,4R,5S)-3,4-dihydroxy-2,5-dihydroxymethyl pyrrolidine from l-sorbose

  摘要：

  One of the most frequently synthesized iminosugar derivatives is DMDP. Starting from L-sorbose, a practical method for the synthesis of derivatives of this five-membered iminocyclitol has been developed, involving straightforward steps and a convenient selective reduction of a ketoxime intermediate. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2013.03.017