6-[3-(4-chlorophenoxy)-phenyl]-5,6-dihydropyrimidine-2,4-dione | 651718-07-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-[3-(4-chlorophenoxy)-phenyl]-5,6-dihydropyrimidine-2,4-dione
• 英文别名: 6-[3-(4-Chlorophenoxy)phenyl]dihydropyrimidine-2,4(1H,3H)-dione；6-[3-(4-chlorophenoxy)phenyl]-1,3-diazinane-2,4-dione
• CAS: 651718-07-9
• 化学式: C₁₆H₁₃ClN₂O₃
• 分子量: 316.744
• InChiKey: FSGJFPIWXFWIFG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  67.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• US7501429B2
  申请人：——

  公开号：US7501429B2

  公开（公告）日：2009-03-10
• [EN] DIHYDROURACIL COMPOUNDS AS ANTI-ICTOGENIC OR ANTI-EPILEPTOGENIC AGENTS<br/>[FR] COMPOSES DE DIHYDRO-URACILE UTILISES COMME AGENTS ANTI-ICTOGENES OU ANTI-EPILEPTOGENES
  申请人：UNIV KINGSTON

  公开号：WO2004009559A2

  公开（公告）日：2004-01-29

  Methods and compounds useful for the inhibition of convulsive disorders, including epilepsy, are disclosed. The methods and compounds of the invention inhibit or prevent or treat ictogenesis, epileptogenesis, or epileptogenesis-associated conditions. Methods for preparing the compounds of the invention are also described. Particularly preferred compounds of the invention include Formula 1 as described herein.