4,5-diamino-1-(4'-chlorobenzyl)pyrazole hydrosulfate | 157469-74-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,5-diamino-1-(4'-chlorobenzyl)pyrazole hydrosulfate
• 英文别名: 1-(4-Chlorobenzyl)-1H-pyrazole-4,5-diamine sulfate；2-[(4-chlorophenyl)methyl]pyrazole-3,4-diamine;sulfuric acid
• CAS: 157469-74-4
• 化学式: C₁₀H₁₁ClN₄*H₂O₄S
• 分子量: 320.757
• InChiKey: IOKLBFFWDKOTAH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  153
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  5-benzylamino-3-bromo-1-(4'-chlorobenzyl)-4-nitropyrazole 以82%的产率得到4,5-diamino-1-(4'-chlorobenzyl)pyrazole hydrosulfate
  参考文献：
  名称：

  Composition for the oxidative dyeing of hair containing

  摘要：

  这是一种用于氧化染发的配方，基于开发剂和偶联剂的组合，其中作为开发剂的有4,5-二氨基-1-(4'-甲氧基苯基)吡唑、4,5-二氨基-1-(4'-甲基苯基)吡唑、4,5-二氨基-1-(4'-氯苯基)吡唑、4,5-二氨基-1-(3'-甲氧基苯基)吡唑、4-氨基-1-(4'-甲氧基苯基)-5-甲基氨基吡嗪或4-氨基-5-(2'-羟乙基)氨基-1-(4'-甲氧基苯基)吡嗪。

  公开号：

  US05534267A1

文献信息

• Oxidation hair dye composition based on 4,5-diaminopyrazole and
  申请人：Wella Aktiengesellschaft

  公开号：US05718731A1

  公开（公告）日：1998-02-17

  The oxidation hair dye composition contains from 0.01 to 4.0 percent by weight of a developer substance including at least one diaminopyrazole of the formula (I) ##STR1## wherein R.sup.1 is selected from the group consisting of hydrogen, an alkyl group having from 1 to 6 carbon atoms, a hydroxyalkyl group having from 2 to 4 carbon atoms and a substituted or unsubstituted benzyl group, and R.sup.2 and R.sup.3, independently, are each selected from the group consisting of hydrogen, an alkyl group having from 1 to 6 carbon atoms and a hydroxyalkyl group having from 2 to 4 carbon atoms; and from 0.01 to 4.0 percent by weight of a coupler substance including at least one m-phenylenediamine selected from the group consisting of N-(3-dimethylamino)phenyl urea and 3-(N-methylsulfonyl)amino-N,N-dimethylaniline.

  这种氧化染发剂组合物包含0.01至4.0重量百分比的发色剂物质，其中包括至少一种式(I)的二氨基吡唑，式中R1从氢、具有1至6个碳原子的烷基、具有2至4个碳原子的羟基烷基和取代或未取代的苄基组成的群中选择，而R2和R3各自独立地从氢、具有1至6个碳原子的烷基和具有2至4个碳原子的羟基烷基组成的群中选择；以及0.01至4.0重量百分比的偶联剂物质，其中包括至少一种从N-(3-二甲基氨基苯基)脲和3-(N-甲基磺酰基)氨基-N，N-二甲基苯胺中选择的m-苯二胺。
• Composition for colouring hair
  申请人：Beauty & Business S.p.A.

  公开号：US10105301B2

  公开（公告）日：2018-10-23

  The present invention describes a composition for coloring hair, comprising at least one dye having the formula (I) and at least one dye having the formula (II): where the groups are defined in the description. The composition provides hair colorings stable and brilliant at various pH values and also resistant to washing.

  本发明描述了一种用于染发的组合物，它包含至少一种具有式（I）的染料和至少一种具有式（II）的染料： 其中的基团在描述中定义。 该组合物在各种 pH 值下都能提供稳定、亮丽的染发效果，并且耐洗。
• Composition for colouring keratin fibres
  申请人：Beauty & Business S.p.A.

  公开号：US10639257B2

  公开（公告）日：2020-05-05

  The present invention refers to a hair dye comprising a) an alkalinising agent consisting of at least one amino acid having a pKa of greater than 10.00 and at least one ester of a fatty acid and glycerol polyethoxylate; and b) at least one oxidation colourant. In particular, the composition of the invention does not comprise any further alkalinizing agent. Kits and methods for colouring hair based on this composition also fall within the scope of this invention.

  本发明指的是一种染发剂，它包含 a) 碱化剂，由至少一种 pKa 大于 10.00 的氨基酸和至少一种脂肪酸与甘油聚氧乙烯醚的酯组成；以及 b) 至少一种氧化着色剂。尤其是，本发明的组合物不包含任何进一步的碱化剂。 基于本发明组合物的染发试剂盒和方法也属于本发明的范围。
• Long lasting cosmetic composition comprising silicone elastomer
  申请人：DOW SILICONES CORPORATION

  公开号：US10918587B2

  公开（公告）日：2021-02-16

  A composition is provided that includes an elastomer and an additive. The additive stabilizes the elastomer, although it may be useful for an alternate or additional purpose. The elastomer can have a moiety according to the general formula: A-B-A or B-A-B. Each A independently comprises a polysiloxane moiety having at least two siloxy (Si—O) groups. Each B independently comprises a moiety, or a precursor thereof, having at least one carboxyl group. B is bonded to a silicon atom in A. The elastomer may comprise the reaction product of a reaction of: a first component having at least one reactive group; a second component having at least one reactive group; and a third component having at least two reactive groups reactive with the reactive groups of the first and second components. In addition, a cosmetic composition is provided that includes the elastomer, the additive, and at least one cosmetic component.

  提供了一种包括弹性体和添加剂的组合物。添加剂可稳定弹性体，但也可用于其他目的。弹性体可以具有符合通式的分子：A-B-A 或 B-A-B。每个 A 独立包含一个聚硅氧烷分子，该分子至少有两个硅氧（Si-O）基团。每个 B 都独立地包含一个具有至少一个羧基的分子或其前体。弹性体可包括以下反应的反应产物：具有至少一个活性基团的第一组分；具有至少一个活性基团的第二组分；以及具有至少两个与第一和第二组分的活性基团反应的活性基团的第三组分。此外，还提供了一种化妆品组合物，其中包括弹性体、添加剂和至少一种化妆品成分。
• Keratin fiber dyeing composition
  申请人：BEAUTY & BUSINESS S.p.A.

  公开号：US11160737B2

  公开（公告）日：2021-11-02

  Disclosed are hair-colouring compositions comprising an oxidative dye and an alkalising agent consisting of isopropanolamine and a malic acid diester. The compositions according to the invention, due to synergic effects between isopropanolamine and the malic acid diester, are advantageous, because they lighten the hair by up to four levels, do not have an unpleasant odour, and limit the damage caused to the hair, maintaining its integrity and consequently its natural characteristics of elasticity, shine and combability.

  本发明公开了一种染发组合物，该组合物包含一种氧化染料和一种碱化剂，碱化剂由异丙醇胺和苹果酸二酯组成。由于异丙醇胺和苹果酸二酯之间的协同作用，本发明的组合物具有以下优点：可将头发的亮度提高四个等级，没有难闻的气味，限制了对头发造成的损害，保持了头发的完整性，从而保持了头发的弹性、光泽和梳理性等天然特性。