3-Isopropyl-4-oxo-thiazolidin | 51672-61-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 3-Isopropyl-4-oxo-thiazolidin
• 英文别名: 3-isopropyl-thiazolidin-4-one；3-Propan-2-yl-1,3-thiazolidin-4-one
• CAS: 51672-61-8
• 化学式: C₆H₁₁NOS
• 分子量: 145.225
• InChiKey: NZCQZDQRQXVBJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  45.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• FACTOR XA INHIBITORS
  申请人：Song Yonghong

  公开号：US20070259924A1

  公开（公告）日：2007-11-08

  The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to intermediates used in making such compounds, pharmaceutical compositions containing such a compound, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.

  本发明涉及式(I)的化合物及其药学上可接受的盐、酯和前药，这些化合物是Xa因子的抑制剂。本发明还涉及用于制备这类化合物的中间体，含有这种化合物的药物组合物，预防或治疗一系列以不良血栓形成为特征的疾病的方法，以及抑制血样凝血的方法。
• PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：US20210047291A1

  公开（公告）日：2021-02-18

  Compounds of the formula (I) wherein the substituents are as defined in claim 1 . Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and to the use of the compounds or compositions 10 in agriculture or horticulture for combating, preventing or controlling animal pests, including arthropods and in particular insects or representatives of the order Acarina.
• METHODS AND COMPOSITIONS FOR TREATING CANCER
  申请人：Engine Biosciences Pte. Ltd.

  公开号：US20220356494A1

  公开（公告）日：2022-11-10

  The present disclosure provides lethal gene pair targets for cancer treatment, along with methods and compositions for regulating their expression and activity. Gene pairs disclosed herein include tyrosine kinase genes (e.g., SRC, RON, and YES). Also provided are methods and compositions for regulating tyrosine kinase activity, including RON specific pyrazole benzamide inhibitors and methods for gene regulation.
• US7763608B2
  申请人：——

  公开号：US7763608B2

  公开（公告）日：2010-07-27
• US7767697B2
  申请人：——

  公开号：US7767697B2

  公开（公告）日：2010-08-03