| 1603829-39-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1603829-39-5
• 化学式: Br*C₁₉H₁₈NO₂
• 分子量: 372.261
• InChiKey: JMWLCPIOHVXJGC-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.33
• 重原子数：
  23.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  30.18
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  在 正丁基锂 、 四甲基乙二胺 、 potassium carbonate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 5.25h， 生成 2-(6-methoxynaphthalen-2-yl)-5-(p-tolyl)indolizine
  参考文献：
  名称：

  Synthesis, photophysical, and electrochemical properties of 2,5-diaryl-indolizines

  摘要：

  A variety of novel 2,5-dialyl-indolizines have been prepared through the palladium-catalyzed cross-coupling reactions of organozinc reagents prepared from 2-aryl-indolizines with aromatic halides. The photophysical properties of representative compounds indicate that the 2,5-diaryl-indolizines are promising candidates to be used in optoelectronic devices and biomolecular labeling. In addition, cyclic voltammetry studies of some nitrophenyl-substituted indolizines have shown evidences of an oxidation process without the correspondent reduction peak suggesting a dimerization reaction. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.11.105
• 作为产物：
  描述：

  碳酸甲丙酯 、 2-(溴乙酰基)-6-甲氧基萘 以 丙酮 为溶剂， 反应 4.0h， 生成
  参考文献：
  名称：

  Synthesis, photophysical, and electrochemical properties of 2,5-diaryl-indolizines

  摘要：

  A variety of novel 2,5-dialyl-indolizines have been prepared through the palladium-catalyzed cross-coupling reactions of organozinc reagents prepared from 2-aryl-indolizines with aromatic halides. The photophysical properties of representative compounds indicate that the 2,5-diaryl-indolizines are promising candidates to be used in optoelectronic devices and biomolecular labeling. In addition, cyclic voltammetry studies of some nitrophenyl-substituted indolizines have shown evidences of an oxidation process without the correspondent reduction peak suggesting a dimerization reaction. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.11.105