1-Ethyl-4-thiocyanato-benzene | 35293-47-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 1-Ethyl-4-thiocyanato-benzene
• 英文别名: (4-Ethylphenyl) thiocyanate
• CAS: 35293-47-1
• 化学式: C₉H₉NS
• 分子量: 163.243
• InChiKey: PVFWMVNOJFSGJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  49.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  potassium thioacyanate 、 以 水 为溶剂， 生成 1-Ethyl-4-thiocyanato-benzene
  参考文献：
  名称：

  Photochemical Thiocyanation of Aromatic Compounds¹

  摘要：

  DOI：

  10.1055/s-1972-21825

文献信息

• [EN] CHELATORS AND METHODS OF MAKING AND USING SAME<br/>[FR] CHÉLATEURS ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
  申请人：UNIV BRITISH COLUMBIA

  公开号：WO2020186328A1

  公开（公告）日：2020-09-24

  A chelating agent having the general formula (I) is provided (I) Metal chelates and constructs for carrying out targeted radionuclide therapy incorporating such chelating agents are provided. Methods of making and using the chelating agent, metal chelates and constructs for carrying out targeted radionuclide therapy, as well as diagnostic and therapeutic methods using such constructs, are provided.

  提供了具有一般公式（I）的螯合剂（I），提供了金属螯合物和用于进行靶向放射性核素治疗的构造物。提供了制备和使用螯合剂、金属螯合物和构造物进行靶向放射性核素治疗的方法，以及使用这些构造物的诊断和治疗方法。
• Benzoxazole Derivatives Having Inhibitory Activity Against Interleukin-6, Preparation Method Thereof, and Pharmaceutical Composition Containing the Same
  申请人：Park Choo Hea Young

  公开号：US20130090480A1

  公开（公告）日：2013-04-11

  The present invention relates to benzoxazole derivatives represented by the Formula 1, which has an inhibitory activity against interleukin-6 (IL-6), a method for preparation thereof, and a pharmaceutical composition containing the same. The compound represented by the Formula 1 according to the present invention has a superior inhibitory activity against interleukin-6, and therefore, can be practically applied for prevention and treatment of diseases caused by abnormal interleukin-6 activity.

  本发明涉及由公式1表示的苯并噁唑衍生物，其具有对白细胞介素-6（IL-6）的抑制活性，以及其制备方法和含有该化合物的药物组合物。根据本发明的公式1所表示的化合物具有优越的抑制白细胞介素-6的活性，因此，可以实际应用于预防和治疗由异常白细胞介素-6活性引起的疾病。
• BIREFRINGENT LIQUID CRYSTAL COMPOSITION COMPRISING ALKYLSULFANYLARYL ISOTHIOCYANATO TOLANE COMPOUNDS
  申请人：Essilor International

  公开号：EP3394206B1

  公开（公告）日：2021-05-05
• PICOLINATE CROSS-BRIDGED CYCLAMS, CHELATES WITH METALLIC CATIONS AND USE THEREOF
  申请人：UNIVERSITÉ DE BRETAGNE OCCIDENTALE

  公开号：US20160287733A1

  公开（公告）日：2016-10-06

  Chelates resulting from the complexation of picolinate cross-bridged cyclams of formula (I), wherein n and the substituents L1-L4 and R1-R5 are as defined, with metallic cations. Picolinate cross-bridged cyclam ligands of formula (I), the use of chelates in nuclear medicine and the use of ligands in cations detection or epuration of effluents are also described.
• BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

  公开号：US20170326261A1

  公开（公告）日：2017-11-16

  Disclosed are chelates resulting from the complexation of bifunctional do2pa derivatives ligands of formula (I), wherein the substituents R 1 , R 1′ , R 2 , R 2′ , R 3 , R 3′ , L 1 , L 1′ , L 2 and L 2′ are defined as in the claims, with metallic cations, especially Pb(II) and Bi(III). Also disclosed are bifunctional do2pa derivatives ligands of formula (I), as well as the use of chelates in nuclear medicine and the use of ligands in cations detection or epuration of effluents.