2,3,6-Trichloro-5-fluoropyridine | 52208-51-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,3,6-Trichloro-5-fluoropyridine
• CAS: 52208-51-2
• 化学式: C₅HCl₃FN
• 分子量: 200.42
• InChiKey: PNUFNUKKIACNMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS
  申请人：Vymed Corporation

  公开号：US20140073631A1

  公开（公告）日：2014-03-13

  Disclosed are guanidine and biguanidine derivatives which have anti-viral and antibacterial activity. Also disclosed are pharmaceutical compositions containing such compounds as an active ingredient, and anti-viral and anti-bacterial methods utilizing such compounds. Methods of treating infections using the guanidine and biguanidine derivatives are also disclosed.

  本文披露了具有抗病毒和抗菌活性的胍和双胍衍生物。还披露了含有这些化合物作为活性成分的药物组合物，以及利用这些化合物的抗病毒和抗菌方法。还披露了使用胍和双胍衍生物治疗感染的方法。
• PYRIDINES AND PYRIDINE N-OXIDES AS MODULATORS OF THROMBIN
  申请人：Player R. Mark

  公开号：US20070225282A1

  公开（公告）日：2007-09-27

  The present invention describes compounds of Formula I: wherein W, X, Y, Z, and Q are defined herein, or a pharmaceutically acceptable salt thereof, for the prophylaxis, or treatment of diseases and conditions related to thrombin activity in a mammal.

  本发明描述了以下式I的化合物：其中W、X、Y、Z和Q在此处定义，或其药学上可接受的盐，用于在哺乳动物中预防或治疗与凝血酶活性相关的疾病和症状。
• Antiviral and antimicrobial guanidine or biguanidine derivatives
  申请人：——

  公开号：US20040132993A1

  公开（公告）日：2004-07-08

  Disclosed are guanidine and biguanidine derivatives which have anti-viral and anti-bacterial activity. Also disclosed are pharmaceutical compositions containing such compounds as an active ingredient, and anti-viral and anti-bacterial methods utilizing such compounds.

  本发明涉及具有抗病毒和抗细菌活性的胍和双胍衍生物。还公开了包含此类化合物作为活性成分的药物组合物，以及利用此类化合物的抗病毒和抗细菌方法。
• Naphthyridine antianaerobic compounds
  申请人：ABBOTT LABORATORIES

  公开号：EP0302372B1

  公开（公告）日：1992-12-16
• ANTIVIRAL AND ANTIMICROBIAL GUANIDINE OR BIGUANIDINE DERIVATIVES
  申请人：Shetty, B. Vithal

  公开号：EP1406619A1

  公开（公告）日：2004-04-14