1-(β-Ethoxycarbonylallylamino)-anthrachinon | 29822-60-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1-(β-Ethoxycarbonylallylamino)-anthrachinon
• 英文别名: Ethyl 2-[[(9,10-dioxoanthracen-1-yl)amino]methyl]prop-2-enoate
• CAS: 29822-60-4
• 化学式: C₂₀H₁₇NO₄
• 分子量: 335.359
• InChiKey: GSXYURDXIGXGHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  72.5
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS
  申请人：Satake Kohsuke

  公开号：US20130202551A1

  公开（公告）日：2013-08-08

  An ionic compound capable of providing a cured material having superior antibacterial property and oxygen permeability, and a composition containing the ionic compound, and a cured material, a hydro gel and an ophthalmic lens which have long-term sustainable antibacterial property and superior oxygen permeability. The ionic compound is represented by the following formula (1): In formula (1), P represents a polymerizable functional group. Q + represents a cationic group: Z represents an n-valent siloxanyl group in which the total atomic weight of a group of constituent atoms is no less than 70 and no greater than 1,000; X m− represents an m-valent anion; and n is an integer of 1 to 10, where provided that n is no less than 2, a plurality of P3 and Q + 3 are each independently as defined above.

  一种离子化合物，能够提供具有优越抗菌性能和氧透性的固化材料，以及含有该离子化合物的组合物，以及具有长期可持续抗菌性能和优越氧透性的固化材料、水凝胶和眼镜片。该离子化合物由以下式（1）表示： 在式（1）中，P代表可聚合的功能基团。Q + 代表阳离子基团：Z代表一个n价硅氧烷基团，其中构成原子的总原子量不小于70且不大于1,000；X m− 代表m价阴离子；n为1至10的整数，其中n不小于2时，多个P3和Q + 3分别独立定义如上所述。
• STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS
  申请人：KOWA COMPANY, LTD.

  公开号：US20150094439A1

  公开（公告）日：2015-04-02

  A polymerizable UV-absorbing colorant monomer is provided, which is excellent in stability under alkaline conditions and which is available for a useful material polymer for an intraocular lens. A compound, which is represented by the following general formula (1), is used as a polymerizable UV-absorbing monomer available for a material polymer for an intraocular lens: (in the general formula (1), R 1 is a hydrogen atom, a hydroxy group, a carboxy group, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, a sulfonic acid group, or a benzyloxy group, R 2 is a hydrogen atom, a hydroxy group, or an alkoxy group having 1 to 4 carbon atoms, and R 3 is represented by the following formula (2)): (in the general formula (2), R 4 is a hydrogen atom or a methyl group, and R 5 is a single bond or an alkylene group having 1 to 4 carbon atoms which may have a substituent or substituents.)

  提供一种可聚合的吸收紫外线颜料单体，其在碱性条件下稳定性优良，并可用作人工晶体的有用材料聚合物。 一种化合物，其由以下通用式（1）表示，用作人工晶体的材料聚合物的可聚合吸收紫外线单体：（在通用式（1）中，R1是氢原子、羟基、羧基、具有1至8个碳原子的烷基、具有1至8个碳原子的烷氧基、磺酸基或苄氧基，R2是氢原子、羟基或具有1至4个碳原子的烷氧基，R3由以下式（2）表示）：（在通用式（2）中，R4是氢原子或甲基基团，R5是单键或具有1至4个碳原子的烷基基团，可能具有取代基或取代基。）
• Silicon-containing compound and ocular lens material
  申请人：Menicon Co., Ltd.

  公开号：EP0781777A1

  公开（公告）日：1997-07-02

  A silicon-containing compound of the formula (I): wherein R1 is a C1-6 alkylene group; A is a group of the formula (II): wherein R2 is a hydrogen atom or a methyl group, R3 is a C1-6 trivalent hydrocarbon group or a C1-6 bivalent hydrocarbon group when R4 is a hydrogen atom, and R4 is a hydrogen atom, a hydroxyl group, a C1-6 alkyl group or a group of the formula (III): wherein R5 is a C1-6 alkylene group, and m is an integer of from 1 to 15, or a group of the formula (IV): wherein R6 is a hydrogen atom or a methyl group, and R7 is a direct bond or a C1-6 alkylene group; and n is an integer of from 1 to 15.

  化合物的化学式为（I）：其中R1是C1-6烷基；A是化学式（II）的基团：其中R2是氢原子或甲基基团，R3是C1-6三价碳氢基团或C1-6二价碳氢基团（当R4是氢原子时），而R4是氢原子、羟基、C1-6烷基或化学式（III）的基团：其中R5是C1-6烷基，m是1至15的整数，或化学式（IV）的基团：其中R6是氢原子或甲基基团，R7是直接键或C1-6烷基，n是1至15的整数。
• Soft ocular lens material
  申请人：Menicon Co., Ltd.

  公开号：EP0379146A2

  公开（公告）日：1990-07-25

  A soft ocular lens material made of a copolymer consisting essentially of: (A) from 5 to 70 parts by weight of a fluorine-­containing (meth)acrylate; (B) from 5 to 60 parts by weight of an alkyl (meth)acrylate; (C) from 3 to 45 parts by weight of a polysiloxane macromonomer having polymerizable groups at both terminals, of the formula I: wherein each of Y¹¹ and Y¹² independently represents an acryloyl group, a methacryloyl group, a vinyl group or an allyl group; each of X¹¹ and X¹² independently represents a covalent bond, an oxygen atom or an alkylene glycol group; each of R¹¹ and R¹² independently represents a linear or branched alkylene group having from 1 to 6 carbon atoms; each of R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷ and R¹⁸ independently represents an alkyl group having from 1 to 3 carbon atoms or a phenyl group; i is an integer of from 1 to 1500; and j is an integer of from 0 to 1499 (provided that i+j is at most 1500); and (D) from 3 to 40 parts by weight of a polysiloxane macromonomer having polymerizable groups bonded via one or two urethane bonds to the siloxane main chain, of the formula II: wherein each of Y²¹ and Y²² independently represents a group selected from the group consisting of an acryloyloxy group, a methacryloyloxy group, a vinyl group and an allyl group; each of R³¹ and R³⁴ independently represents a linear or branched alkylene group having from 2 to 6 carbon atoms; each of X²¹ and X²² independently represents a covalent bond, an oxygen atom or an alkylene glycol group; each of R³² and R³³ independently represents a linear or branched alkylene group having from 1 to 6 carbon atoms; each of R²³, R²⁴, R²⁵, R²⁶, R²⁷ and R²⁸ independently represents an alkyl group having from 1 to 3 carbon atoms or a phenyl group; each of E²¹ and E²² independently represents -NHCO- (provided that in this case, each of X²¹ and X²² is a covalent bond, E²¹ forms a urethane bond together with X²⁵, and E²² forms a urethane bond together with X²⁶) or a bivalent group derived from a diisocyanate selected from the group consisting of saturated aliphatic, alicyclic and aromatic diisocyanates (provided that in this case, each of X²¹ and X²² independently represents an oxygen atom or an alkylene glycol group, E²¹ forms a urethane bond together With X²¹ and X²⁵, and E²² forms a urethane bond together with X²² and X²⁶); each of X²⁵ and X²⁶ independently represents an oxygen atom, an alkylene glycol or a group represented by the formula V: wherein R⁴¹ is a trivalent hydrocarbon group having from 1 to 6 carbon atoms; Y²³ represents a group selected from the group consisting of an acryloyloxy group, a methacryloyloxy group, a vinyl group and a allyl group; R³⁶ represents a linear or branched alkylene group having from 2 to 6 carbon atoms; X²³ represents a covalent bond, an oxygen atom or an alkylene glycol group; E²³ represents -NHCO- (provided that in this case, X²³ is a covalent bond) or a bivalent group derived from a diisocyanate selected from the group consisting of saturated aliphatic, alicyclic and aromatic diisocyanates (provided that in this case, X²³ is an oxygen atom or an alkylene glycol group), which forms a urethane bond together with X²³ and the adjacent oxygen atom bonded to R⁴¹; a is an integer of from 1 to 1500; and b is an integer of from 0 to 1499, provided a+b ≦ 1500; as essential copolymer components.

  一种由共聚物制成的软性眼透镜材料，其主要成分包括 (A) 5 至 70 份(重量)含氟(甲基)丙烯酸酯； (B) 5 至 60 份（按重量计）烷基（甲基）丙烯酸酯； (C) 3 至 45 份（按重量计）在两端具有可聚合基团的聚硅氧烷大单体，其式为 I： 其中 Y¹¹ 和 Y¹² 各自独立地代表丙烯酰基、甲基丙烯酰基、乙烯基或烯丙基； X¹¹ 和 X¹² 各自独立地代表共价键、氧原子或亚烷基二醇基； R¹¹ 和 R¹² 各自独立地代表具有 1 至 6 个碳原子的直链或支链亚烷基；R¹³、R¹⁴、R¹⁵、R¹⁶、R¹⁷ 和 R¹⁸ 各自独立地代表具有 1 至 3 个碳原子的烷基或苯基； i 是 1 至 1500 的整数；和 j 是 0 至 1499 的整数（条件是 i+j 至多为 1500）；和 (D) 3 至 40 份(重量)的聚硅氧烷大单体，其可聚合基团通过一个或两个 聚氨酯键与硅氧烷主链结合，如式 II 所示： 其中 Y²¹ 和 Y²² 各自独立地代表选自丙烯酰氧基、甲基丙烯酰氧基、乙烯基和烯丙基的基团； R³¹ 和 R³⁴ 各自独立地代表具有 2 至 6 个碳原子的直链或支链亚烷基；X²¹和X²²各自独立地代表共价键、氧原子或烯二醇基团；R³²和R³³各自独立地代表具有1至6个碳原子的直链或支链亚烷基；R²³、R²⁴、R²⁵、R²⁶、R²⁷和R²⁸各自独立地代表具有1至3个碳原子的烷基或苯基；E²¹ 和 E²² 中的每一个独立地代表-NHCO-（条件是在这种情况下，X²¹ 和 X²² 中的每一个是共价键，E²¹ 与 X²⁵ 一起形成氨基甲酸乙酯键，E²² 与 X²⁶ 一起形成氨基甲酸乙酯键）或衍生自二异氰酸酯的二价基团，该二异氰酸酯选自由饱和脂肪族、脂环族和芳香族二异氰酸酯组成的组、或衍生自二异氰酸酯的二价基团，该二异氰酸酯选自饱和脂肪族、脂环族和芳香族二异氰酸酯（条件是在这种情况下，X²¹ 和 X²² 各自独立地代表氧原子或亚烷基二醇基团，E²¹ 与 X²¹ 和 X²⁵ 形成氨基甲酸乙酯键，E²² 与 X²² 和 X²⁶ 形成氨基甲酸乙酯键）；X²⁵ 和 X²⁶ 各自独立地代表氧原子、亚烷基二醇或式 V 所代表的基团： 其中 R⁴¹ 是具有 1 至 6 个碳原子的三价烃基；Y²³ 代表选自丙烯酰氧基、甲基丙烯酰氧基、乙烯基和烯丙基的基团；R³⁶ 代表具有 2 至 6 个碳原子的直链或支链亚烷基；X²³ 代表共价键、氧原子或亚烷基二醇基团；E²³代表-NHCO-（条件是在这种情况下，X²³是共价键）或二异氰酸酯衍生的二价基团，该二异氰酸酯选自饱和脂肪族、脂环族和芳香族二异氰酸酯（条件是在这种情况下，X²³是氧原子或亚烷基二醇基）组成的组，它与 X²³和与 R⁴¹ 结合的相邻氧原子一起形成氨基甲酸酯键；a 是 1 至 1500 的整数；b 是 0 至 1499 的整数，条件是 a+b ≦ 1500； 作为共聚物的基本成分。
• Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production
  申请人：Menicon Co., Ltd.

  公开号：EP0770888A2

  公开（公告）日：1997-05-02

  A substantially non-crosslinked low water-absorptive ocular lens material obtained by polymerizing polymerizable components comprising a methoxysilane compound (A) of the formula (I):         X-Z-Si(OCH3)n(R1)3-n     (I) wherein X is a (meth)acryloyloxy group, a vinyl group, a group of the formula or an allyl group, Z is a direct bond or a C1-3 alkylene group, R1 is a C1-6 alkyl group, and n is an integer of from 1 to 3, and a hydrophobic silicon-containing monomer (B) which is copolymerizable with the methoxysilane compound (A) and which undergoes no crosslinking reaction.

  一种基本无交联的低吸水率眼晶状体材料，通过聚合由式 (I) 的甲氧基硅烷化合物 (A) 组成的可聚合组分而获得： X-Z-Si(OCH3)n(R1)3-n (I) 其中 X 是(甲基)丙烯酰氧基、乙烯基、式中的基团或烯丙基； Z 是(甲基)丙烯酰氧基、乙烯基、式中的基团或烯丙基。 或烯丙基，Z 为直接键或 C1-3 亚烷基，R1 为 C1-6 烷基，n 为 1-3 的整数，以及可与甲氧基硅烷化合物（A）共聚且不发生交联反应的疏水性含硅单体（B）。