4-methyl-6,7-dihydro-5H-cyclopenta[c]pyridine | 83504-32-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-methyl-6,7-dihydro-5H-cyclopenta[c]pyridine
• CAS: 83504-32-9
• 化学式: C₉H₁₁N
• 分子量: 133.19
• InChiKey: DNOMTIGKEMICLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• NOVEL METHODS FOR PREPARATION OF SUBSTITUTED PYRIDINES AND RELATED NOVEL COMPOUNDS
  申请人：Watkins Edmond Blake

  公开号：US20200095245A1

  公开（公告）日：2020-03-26

  The present invention relates to novel methods of preparation of substituted pyridines and the compounds produced therefrom. In particular, the present invention provides efficient methods for the construction of diversely substituted pyridines, with varying substitution patterns under simple and metal-free conditions with high atom- and pot-economy and excellent functional group tolerance, and which are useful for the synthesis of natural products.

  本发明涉及取代吡啶的新的制备方法及其由此产生的化合物。特别是，本发明提供了一种高效的方法，用于构建不同取代的吡啶，具有不同的取代模式，在简单和无金属条件下具有高原子经济和锅经济以及优良的功能团耐受性，并且适用于天然产物的合成。
• NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS
  申请人：Roberts Edward

  公开号：US20100010001A1

  公开（公告）日：2010-01-14

  Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-4-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.

  提供了激活1型鞘氨醇-1-磷酸受体的化合物。某些化合物在与鞘氨醇-4-磷酸受体亚型3相比，选择性地激活受体亚型1。提供了用于治疗需要医学上激活、激动、抑制或拮抗S1P1的恶性疾病的创新化合物的用途和方法。
• NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND BACTERICIDE FOR AGRICULTURAL AND HORTICULTURAL USE
  申请人：Nippon Soda Co., Ltd.

  公开号：EP2223919A1

  公开（公告）日：2010-09-01

  The present invention provides a nitrogen-containing heterocyclic compound represented by the formula (I) (wherein, A-B represents any one of the formula (II): C=N, the formula (III): CH-NR9 and the formula (IV): N-C(=Y); R1, R2, R3 and R4 independently represent hydrogen atom, a halogen atom, a C1-20 alkyl group or the like; R5, R6, R7 and R8 independently represent hydrogen atom, a halogen atom, a C1-20 alkyl group or the like; X represents a halogen atom or the like; and n represents an integer of 0 to 4; in the formula (III), R9 represents hydrogen atom, a C1-20 alkyl group or the like; in the formula (IV), Y represents oxygen atom or sulfur atom.) and the salt thereof. The present invention also provides a fungicide for agricultural and horticultural use containing at least one of the said nitrogen-containing heterocyclic compound or the salt thereof as an active ingredient.

  本发明提供了一种由式(I)代表的含氮杂环化合物（其中，A-B代表式(II)中的任意一种：C=N、式(III)：CH-NR9和式(IV)中的任意一种：N-C(＝Y)；R1、R2、R3和R4独立地代表氢原子、卤素原子、C1-20烷基或类似物；R5、R6、R7和R8独立地代表氢原子、卤素原子、C1-20烷基或类似物；X代表卤素原子或类似物；n代表0至4的整数；在式(III)中，R9代表氢原子、C1-20烷基或类似物；在式(IV)中，Y代表氧原子或硫原子)及其盐。本发明还提供了一种农业和园艺用杀真菌剂，该杀真菌剂含有至少一种上述含氮杂环化合物或其盐作为活性成分。
• Methods for preparation of substituted pyridines and related novel compounds
  申请人：Watkins Edmond Blake

  公开号：US11117893B2

  公开（公告）日：2021-09-14

  The present invention relates to novel methods of preparation of substituted pyridines and the compounds produced therefrom. In particular, the present invention provides efficient methods for the construction of diversely substituted pyridines, with varying substitution patterns under simple and metal-free conditions with high atom- and pot-economy and excellent functional group tolerance, and which are useful for the synthesis of natural products.

  本发明涉及新型取代吡啶及其化合物的制备方法。特别是，本发明提供了在简单和无金属条件下构建具有不同取代模式的多种取代吡啶的有效方法，这些方法具有高原子经济性和高耐受性以及优异的官能团耐受性，可用于天然产物的合成。
• US8466183B2
  申请人：——

  公开号：US8466183B2

  公开（公告）日：2013-06-18