N,N'-propilenbis((ferrocenylmethyl)amine) | 194150-01-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N'-propilenbis((ferrocenylmethyl)amine)
• 英文别名: N,N'-bis(cyclopenta-1,3-dien-1-ylmethyl)propane-1,3-diamine;cyclopenta-1,3-diene;iron(2+)
• CAS: 194150-01-1
• 化学式: C₂₅H₃₀Fe₂N₂
• 分子量: 470.221
• InChiKey: UJFJAEMGCVARIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  六氯环三磷腈 、 N,N'-propilenbis((ferrocenylmethyl)amine) 在 N(CH₂CH₃)3 作用下， 以 四氢呋喃 、 三乙胺 为溶剂， 以66%的产率得到spiro(propane-1,3-diamino)[N,N'-bis(1-ferrocenylmethyl)]-4,4,6,6-tetrachlorocyclotriphosphazatriene
  参考文献：
  名称：

  磷氮化合物。18.新型螺环单-和双-二茂铁基磷腈衍生物的合成，立体异构性质，结构和电化学研究，生物学活性和DNA相互作用

  摘要：

  hexachlorocyclotriphosphazatriene的反应中，N 3 P 3氯6，具有单- （1和2）和bisferrocenyldiamines（3 - 5），FCCH 2 NH（CH 2）Ñ NHR 1（R 1 = H或FCCH 2 - ），产生单- （6和7）和螺bisferrocenylphosphazenes（8 - 10）。完全取代的磷腈（11 - 15和18 - 21）从对应的部分取代的磷腈（的反应得到的6 - 10）与过量的吡咯烷和NH 2（CH 2）3分别ONA。的反应6用1-氮杂-12-冠-4，得到偕（16）和三（17）的冠醚取代的磷腈。化合物的结构研究已通过元素分析，质谱，傅里叶变换IR，1 H，13 C和31 P NMR以及DEPT，COSY，HETCOR和HMBC技术进行了验证。的晶体结构7，10，11，并且已经通过X射线晶体学确定了15。在16和1

  DOI：

  10.1021/ic901039k
• 作为产物：
  描述：

  1,3-丙二胺 、 二茂铁甲醛 、 lithium aluminium tetrahydride 在 水 作用下， 以 四氢呋喃 、 苯 为溶剂， 以82%的产率得到N,N'-propilenbis((ferrocenylmethyl)amine)
  参考文献：
  名称：

  Switching and tuning processes in the interaction of protons with ferrocenyl amines

  摘要：

  Some new ferrocene-functionalized amines have been synthesized and characterized. Electrochemical and potentiometric studies have been carried out in THF:H2O (60:40 v/v) to determine protonation constants of the oxidized and "reduced" species and the oxidation potential shift between pH acid and basic. Some electrochemical studies have also been performed in CH2Cl2:MeOH mixtures, The change in the acidity properties after oxidation and the related redox potential shift after protonation are discussed. (C) 1998 Elsevier Science Ltd.

  DOI：

  10.1016/s0277-5387(98)00351-9

文献信息

• Phosphorus-Nitrogen Compounds: Part 25. Syntheses, Spectroscopic, Structural and Electrochemical Investigations, Antimicrobial Activities, and DNA Interactions of Ferrocenyldiaminocyclotriphosphazenes
  作者：Nuran Asmafiliz、Zeynel Kılıç、Aslı Öztürk、Yasemin Süzen、Tuncer Hökelek、Leyla Açık、Z. Betül Çelik、L. Yasemin Koç、Mehmet Lütfi Yola、Zafer Üstündağ

  DOI：10.1080/10426507.2013.779273

  日期：2013.12.1

  The condensation reactions of hexachlorocyclotriphosphazene (N3P3Cl6) with mono (1 and 2) and bisferrocenyldiamines (3-5 and 7) resulted in the formation of tetrachloro mono- (8 and 9) and bisferrocenylspirocyclotriphosphazenes (10-13). In addition the tetramorpholino mono- (8a and 9a) and bisferrocenylphosphazenes (10a-12a) were obtained from the reactions of the corresponding tetrachlorophosphazenes (8-12) with excess morpholine. The structures of all the phosphazenes were determined using FTIR, MS, H-1, C-13, and P-31 NMR and 2-dimensional NMR techniques. The structures of 9a and 13 were determined by single crystal X-ray diffraction techniques. Cyclic voltammetric investigations of compounds 8a, 9a, and 11a revealed that ferrocene redox centers undergo reversible oxidation. These ferrocenylphosphazenes appear to be quite robust electrochemically. Interactions between the compounds 8a, 9a, 11a, and 12a and pBR322 plasmid DNA were investigated by agarose gel electrophoresis. [Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfer, and Silicon and the Related Elements for the following free supplemental files: Additional text and figures.]