(S)-2-((S)-Cyclohexanesulfinyl)-pent-4-enethioic acid diethylamide | 670223-14-0

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代酰胺
• 英文名称: (S)-2-((S)-Cyclohexanesulfinyl)-pent-4-enethioic acid diethylamide
• CAS: 670223-14-0
• 化学式: C₁₅H₂₇NOS₂
• 分子量: 301.517
• InChiKey: JKMHXSPDLPMWCL-LIRRHRJNSA-N

物化性质

• 沸点：
  443.2±55.0 °C(Predicted)
• 密度：
  1.09±0.1 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  (S)-2-((S)-Cyclohexanesulfinyl)-pent-4-enethioic acid diethylamide 在 Oxone 、 碳酸氢钠 作用下， 以 水 、 丙酮 为溶剂， 生成 (SS,2S)-2-cyclohexylsulfinyl-N,N-diethylpent-4-eneamide
  参考文献：
  名称：

  Asymmetric Induction of the Iodolactonization Reaction of α-Sulfurated γ-Unsaturated Amides

  摘要：

  The 1,3-asymmetric iodolactonization reaction of enantiopure alpha-sulfurated gamma-unsaturated amides has been investigated. With sulfinyl and sulfonyl groups, a poorly stereoselective reaction was observed, whereas with a sulfanyl moiety, the diastereoselectivity can be high as 96:4. The role of the oxygen atom on the sulfur moiety is discussed.

  DOI：

  10.1021/jo035488b
• 作为产物：
  描述：

  2-((R)-Cyclohexanesulfinyl)-N,N-diethyl-thioacetamide 在 cerium(III) chloride 、 叔丁基锂 作用下， 以 四氢呋喃 、 正戊烷 为溶剂， 生成 (S)-2-((S)-Cyclohexanesulfinyl)-pent-4-enethioic acid diethylamide
  参考文献：
  名称：

  Asymmetric Induction of the Iodolactonization Reaction of α-Sulfurated γ-Unsaturated Amides

  摘要：

  The 1,3-asymmetric iodolactonization reaction of enantiopure alpha-sulfurated gamma-unsaturated amides has been investigated. With sulfinyl and sulfonyl groups, a poorly stereoselective reaction was observed, whereas with a sulfanyl moiety, the diastereoselectivity can be high as 96:4. The role of the oxygen atom on the sulfur moiety is discussed.

  DOI：

  10.1021/jo035488b