申请人:——
公开号:US20020115224A1
公开(公告)日:2002-08-22
The present invention relates to a method for the preparation of a miniaturized optical chemical or biochemical sensor device (e.g. bulk optode, etc. for ion sensing), said device comprising a substrate material having a planar surface portion, said planar surface representing a transducer based on an optical phenomenon such as surface plasmon resonance based on evanescent waves, reflection or transmission; said planar surface portion having arranged thereon an multi-analyte array of (bio)chemical sensor dots located at spatially separated predetermined positions of the planar surface, said sensor dots including (i) a polymer matrix, and (ii) one or more (bio)chemical recognition moieties, the method comprising (a) providing a substrate material having a planar surface portion; (b) providing one or more spotting fluid(s); (c) depositing the one or more spotting fluid(s) onto the planar surface portion of the substrate material by means of a pin-printer deposition mechanism (arrayer) and allowing the spotting fluid(s) to consolidate.
本发明涉及一种制备微型光学化学或生化传感器装置(如用于离子传感的散装光电极等)的方法。本发明涉及一种用于制备微型化光学化学或生化传感器装置(如用于离子传感的体式光电二极管等)的方法,所述装置包括具有平面表面部分的基底材料,所述平面表面代表基于光学现象(如基于蒸发波、反射或透射的表面等离子体共振)的换能器;所述平面表面部分上排列有位于平面表面空间上分离的预定位置的(生物)化学传感点的多分析阵列,所述传感点包括 (i) 聚合物基质,和 (ii) 一个或多个(生物)化学识别分子,该方法包括 (a) 提供具有平面表面部分的基底材料;(b) 提供一种或多种点阵液; (c) 通过针刺机沉积机构(阵列器)将一种或多种点阵液沉积到基底材料的平面部分上,并使点阵液固化。