N,N'-二[3-(二甲基氨基)丙基]二硫代草酰胺 | 62778-13-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代酰胺
• 中文名称: N,N'-二[3-(二甲基氨基)丙基]二硫代草酰胺
• 英文名称: N,N'-bis-(3-dimethylaminopropyl)-dithiooxamide
• 英文别名: N,N'-Bis-(3-dimethylamino-propyl)-dithiooxamid；N,N'-Bis(3-dimethylaminopropyl)ethanedithioamide；N,N'-bis[3-(dimethylamino)propyl]ethanedithioamide
• CAS: 62778-13-6
• 化学式: C₁₂H₂₆N₄S₂
• 分子量: 290.497
• InChiKey: OOGWLZNMIJTRFD-UHFFFAOYSA-N

物化性质

• 密度：
  1.1751 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  94.7
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2930909090

制备方法与用途

类别：有毒物品

毒性分级：高毒

急性毒性：

• 腹腔-小鼠 LD50: 100 毫克/公斤

可燃性危险特性：

• 可燃；燃烧时产生有毒的氮氧化物和硫氧化物烟雾

储运特性：

• 库房需保持通风、低温干燥
• 与食品原料分开存放

灭火剂：

• 干粉、泡沫、沙土、二氧化碳、雾状水

反应信息

• 作为反应物：
  描述：

  nickel(II) nitrate hexahydrate 、 N,N'-二[3-(二甲基氨基)丙基]二硫代草酰胺 以 乙醇 、 水 为溶剂， 生成
  参考文献：
  名称：

  Nickel(II) Complexes of N,N'-Disubstituted Dithiooxamides¹

  摘要：

  N,'N'-Dimethyl- (I), N-,N'-dibenzyl- (II), N,N-'-dioctadecyl- (III), N,N'-bis-(2-hydroxyethy1)- (IV), N,N'-bis-(2-acetoxyethyl)- (V) and N,N'-bis-(3-dimethylaminopropyl)-dithiooxamide (VI) formed intensely colored nickel complexes (VII-XII), respectively. N,N'-Dimethyldithiooxamidonickel(II) (VII) is a low polymer whose size and terminal structure are dependent on both the manner of preparation and purification. VII is crystalline and paramagnetic. N,N'-Bis-(2-hydroxy-ethyl)-dithiooxamidonickel(II) (X) was acetylated, but the product (XIV) contains only half the number of acetyl groups of N,N'-bis-(2-acetoxyethyl)-dithiooxamidonickel (II) (XI) prepared directly from V. The reaction of I with trisethyleuediaminenickel(II) ion gave a complex product (XIII) differing from VII. Certain primary alkylamines were found to react with I, and in the case of trisethvlenediaminenickel(II) ion, such reaction may have occurred during the formation of XIII.

  DOI：

  10.1021/ja01502a004
• 作为产物：
  描述：

  N,N-二甲基-1,3-二氨基丙烷 、 二硫代乙酰胺 以 乙醇 为溶剂， 生成 N,N'-二[3-(二甲基氨基)丙基]二硫代草酰胺
  参考文献：
  名称：

  Preparation of Dithiooxamide Derivatives

  摘要：

  DOI：

  10.1021/jo01068a080

文献信息

• Kibbel, H. U.; Kuecken, M.; Peters, E., Journal fur praktische Chemie (Leipzig 1954), 1981, vol. 323, # 1, p. 41 - 48
  作者：Kibbel, H. U.、Kuecken, M.、Peters, E.、Weber, H.

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ni: MVol.C2, 8.15, page 998 - 1009
  作者：

  DOI：——

  日期：——
• Nickel(II) Complexes of N,N'-Disubstituted Dithiooxamides¹
  作者：Richard N. Hurd、George DeLaMater、George C. McElheny、Leroy V. Peiffer

  DOI：10.1021/ja01502a004

  日期：1960.9

  N,'N'-Dimethyl- (I), N-,N'-dibenzyl- (II), N,N-'-dioctadecyl- (III), N,N'-bis-(2-hydroxyethy1)- (IV), N,N'-bis-(2-acetoxyethyl)- (V) and N,N'-bis-(3-dimethylaminopropyl)-dithiooxamide (VI) formed intensely colored nickel complexes (VII-XII), respectively. N,N'-Dimethyldithiooxamidonickel(II) (VII) is a low polymer whose size and terminal structure are dependent on both the manner of preparation and purification. VII is crystalline and paramagnetic. N,N'-Bis-(2-hydroxy-ethyl)-dithiooxamidonickel(II) (X) was acetylated, but the product (XIV) contains only half the number of acetyl groups of N,N'-bis-(2-acetoxyethyl)-dithiooxamidonickel (II) (XI) prepared directly from V. The reaction of I with trisethyleuediaminenickel(II) ion gave a complex product (XIII) differing from VII. Certain primary alkylamines were found to react with I, and in the case of trisethvlenediaminenickel(II) ion, such reaction may have occurred during the formation of XIII.
• Preparation of Dithiooxamide Derivatives
  作者：RICHARD N. HURD、GEORGE De La MATER、GEORGE C. McELHENY、ROBERT J. TURNER、VERNON H. WALLINGFORD

  DOI：10.1021/jo01068a080

  日期：1961.10