[PdMe(Cl)(μ-bis(dimethylphosphino)methane)2PdCl2] | 454658-75-4

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: [PdMe(Cl)(μ-bis(dimethylphosphino)methane)2PdCl2]
• 英文别名: carbanide;chloropalladium(1+);dichloropalladium;dimethylphosphanylmethyl(dimethyl)phosphane
• CAS: 454658-75-4
• 化学式: C₁₁H₃₁Cl₃P₄Pd₂
• 分子量: 606.461
• InChiKey: GMWCJRLPTNJRSF-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
  7.37
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  [Pd2Me4(bis(dimethylphosphino)methane)2] 、 乙酰氯 以 甲醇 、 二氯甲烷 为溶剂， 生成 [Pd2Me2Cl2(bis(dimethylphosphino)methane)2] 、 [PdMe(Cl)(μ-bis(dimethylphosphino)methane)2PdCl2]
  参考文献：
  名称：

  Preparation of Dinuclear Phosphine-Bridged Palladium(II) Species and Their Silica-Bound Analogues as Catalysts for the Cyclization of Aminoalkynes

  摘要：

  Two new dinuclear. palladium complexes, [Pd2Me2Cl2(dmpm)(2)] (4) and [PdMe(Cl)(dmpm)(2)PdCl2] (5), have been prepared and their structures determined by single-crystal X-ray analysis. 5 is an interesting example of a complex with both a cis-PdCl2 center and a trans-MePdCl center, within the same molecule. The reactivity of 4, as well as the previously reported, complexes [Pd2Me2Cl2(dppm)(2)] (1), [Pd-2(mu-CH2)Cl-2(dppm)(2)] (2), and [Pd2Me4(pmpm)(2)] (3), toward, silica have been investigated. The complexes react readily with either, dichloromethane or benzene suspensions of silica to give chemisorbed species, presumably by reaction of the Pd-Me group,with, the O-H bond of the surface silanol groups, in the case of 1, 3 and 4, and protonation of the methylene bridge, in the case of 2. The complexes containing the more basic phosphine, dmpm, gave much higher palladium loadings, (wt % Pd 1.37-2.47) on silica, compared to the dppm complexes (wt % Pd 0.55-0.80). The molecular and grafted materials were initially tested as catalysts for the cyclization of 6-aminohex-1-yne to give 2-methyl-1,2-dehydropiperidine. The silica/dmpm complexes were found to be the most active catalysts for this reaction and were also tested for the cyclization of 5-phenyl-4-pentyn-1-amine.

  DOI：

  10.1021/om020026u