N'-pyridin-3-ylmethanimidamide | 775221-92-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N'-pyridin-3-ylmethanimidamide
• CAS: 775221-92-6
• 化学式: C₆H₇N₃
• mdl: MFCD13175292
• 分子量: 121.142
• InChiKey: ZMMASEOZYFXODV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Engineered receptor and their use
  申请人：University of Pittsburgh—Of the Commonwealth System of Higher Education

  公开号：US10246504B2

  公开（公告）日：2019-04-02

  Engineered chloride channel receptors, nucleic acids encoding these receptors, expression vectors including these nucleic acids are disclosed herein. Nanoparticles and pharmaceutical compositions including these engineered chloride channel receptors, nucleic acids, and expression vectors are disclosed. The use of these compositions and nanoparticles, such as for the treatment of pain, cystic fibrosis and asthma, is also disclosed.

  本文公开了工程化氯离子通道受体、编码这些受体的核酸、包括这些核酸的表达载体。还公开了包括这些工程化氯离子通道受体、核酸和表达载体的纳米颗粒和药物组合物。还公开了这些组合物和纳米颗粒的用途，如用于治疗疼痛、囊性纤维化和哮喘。
• ENGINEERED RECEPTORS AND THEIR USE
  申请人：XU Yan

  公开号：US20150307582A1

  公开（公告）日：2015-10-29

  Engineered chloride channel receptors, nucleic acids encoding these receptors, expression vectors including these nucleic acids are disclosed herein. Nanoparticles and pharmaceutical compositions including these engineered chloride channel receptors, nucleic acids, and expression vectors are disclosed. The use of these compositions and nanoparticles, such as for the treatment of pain, cystic fibrosis and asthma, is also disclosed.
• US9624288B2
  申请人：——

  公开号：US9624288B2

  公开（公告）日：2017-04-18
• [EN] ENGINEERED RECEPTORS AND THEIR USE<br/>[FR] RÉCEPTEURS MODIFIÉS ET LEUR UTILISATION
  申请人：UNIV PITTSBURGH

  公开号：WO2014093251A1

  公开（公告）日：2014-06-19

  Engineered chloride channel receptors, nucleic acids encoding these receptors, expression vectors including these nucleic acids are disclosed herein. Nanoparticles and pharmaceutical compositions including these engineered chloride channel receptors, nucleic acids, and expression vectors are disclosed. The use of these compositions and nanoparticles, such as for the treatment of pain, cystic fibrosis and asthma, is also disclosed.