5-Ethyl-3-pyridinesulfonyl chloride | 1211589-94-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5-Ethyl-3-pyridinesulfonyl chloride
• 英文别名: 5-ethylpyridine-3-sulfonyl chloride
• CAS: 1211589-94-4
• 化学式: C₇H₈ClNO₂S
• mdl: MFCD18256500
• 分子量: 205.66
• InChiKey: SNSBIMPFYIEINH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.285
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• AMINOPYRAZOLE DERIVATIVES USEFUL AS SRC KINASE INHIBITORS
  申请人：Chugai Seiyaku Kabushiki Kaisha

  公开号：EP3312172B1

  公开（公告）日：2020-05-06
• BIARYL DERIVATIVE
  申请人：DAIICHI SANKYO COMPANY, LIMITED

  公开号：US20210355087A1

  公开（公告）日：2021-11-18

  The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the following formula (I): wherein X 1 represents a nitrogen atom or CR 9 , R 1 represents a hydrogen atom, a C 1 -C 6 alkyl group, or a C 1 -C 6 alkoxy group, R 2 represents a halogen atom, R 3 represents a hydrogen atom or a halogen atom, R 4 represents a hydrogen atom or a halogen atom, and R5 represents a C 1 -C 3 alkylsulfonyl group, a substituted C 1 -C 6 alkyl group, a substituted C 1 -C 6 haloalkyl group, a substituted C 1 -C 6 alkoxy group, or a substituted C 1 -C 6 alkylamino group, or a pharmacologically acceptable salt thereof.