ZINC salicylate dihydrate | 112813-15-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ZINC salicylate dihydrate
• 英文别名: zinc;2-hydroxybenzoate;dihydrate
• CAS: 112813-15-7；240128-21-6；60513-10-2；64627-24-3；71882-06-9
• 化学式: C₁₄H₁₄O₈Zn
• 分子量: 375.65
• InChiKey: XQVXBOYZTOKONQ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  吡啶 、 ZINC salicylate dihydrate 以 乙醇 为溶剂， 以26%的产率得到[Zn(Hsal)₂(Py)₂]
  参考文献：
  名称：

  Some complexes derived from zinc salicylate or 3,5-di-tert-butylsalicylate. The crystal structure of (2,2′-bipyridyl)(methanol)(O-salicylato)(O,O′-salicylato)zinc

  摘要：

  The aqua ligands of diaquabis(salicylato)zinc and diaquabis(3,5-di-tert-butylsalicylato)zinc are easily displaced generating related bis-pyridine and 2,2'-bipyridyl complexes. Attempts to recrystallise the tert-butylsalicylate from ethanol resulted in replacement of the aqua ligands by ethanol ligands. The attempted recrystallisation of (2,2'-bipyridyl)bis(salicylato)zinc from methanol led to the isolation of octahedral [Zn(O2CC6H4OH-2)(2)(bipy)(MeOH)] in which one salicylato ligand is coordinated in a monodentate fashion and the other in a bidentate chelating manner, both coordination modes involving carboxylate rather than hydroxyl oxygen coordination. The methanol is strongly bonded trans to a nitrogen, of the chelating 2,2'-bipyridyl and three further intramolecular six-membered hydrogen bonded rings are present, generated from interactions between the carboxyl and hydroxyl groups of the salicylate ligands and the hydroxyl group of the methanol ligand. (C) 1999 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0020-1693(98)00421-6
• 作为产物：
  描述：

  水杨酸 、 zinc(II) sulfate 以 水 为溶剂， 生成 ZINC salicylate dihydrate
  参考文献：
  名称：

  Rissanen, Kari; Valkonen, Jussi; Kokkonen, Pertti, Acta chemica Scandinavica. Series A: Physical and inorganic chemistry, 1987, vol. 41, p. 299 - 309

  摘要：

  DOI：

文献信息

• Mn(II), Co(II), Ni(II) and Zn salicylates: Synthesis, structure and biological properties studies
  作者：Alexey Gusev、Yuriy Baluda、Elena Braga、Mariya Kryukova、Mikhail Kiskin、Elena Chuyan、Marina Ravaeva、Igor Cheretaev、Wolfgang Linert

  DOI：10.1016/j.ica.2021.120606

  日期：2021.12

  Reaction of acetylsalicylic acid (aspirin) (H2L) with Mn(II), Co(II), Ni(II) and Zn acetates allow to obtain salicylates of related metals. The solid-state structures of prepared complexes were determined by single crystal X-ray crystallography and spectroscopic techniques. Zinc, nickel and cobalt(II) complexes are mononuclear and their crystal structures composed of neutral discrete molecules [Zn(sal)2(H2O)2]

  乙酰水杨酸（阿司匹林）（H 2 L）与 Mn(II)、Co(II)、Ni(II) 和 Zn 醋酸盐的反应允许获得相关金属的水杨酸盐。制备的复合物的固态结构通过单晶 X 射线晶体学和光谱技术确定。锌、镍和钴 (II) 配合物是单核的，它们的晶体结构由中性离散分子 [Zn(sal) 2 (H 2 O) 2 ]、[Ni(sal) 2 (H 2 O) 4 ] 和 [Co (盐) 2 (H 2 O) 4] 而锰衍生物具有二维聚合物结构。评估了这些金属配合物的心肺和皮肤微循环活性。特别是，1-4 种复合物显示出的有前景的治疗活性使它们成为开发有前景的药物的潜在候选者。
• Kharitonov, Yu. Ya.; Tuiebakhova, Z. K., Koordinatsionnaya Khimiya, 1983, vol. 9, p. 857 - 870
  作者：Kharitonov, Yu. Ya.、Tuiebakhova, Z. K.

  DOI：——

  日期：——