(S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid monobutyryloxymethyl ester | 145627-24-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid monobutyryloxymethyl ester
• CAS: 145627-24-3
• 化学式: C₂₀H₂₂N₂O₈
• 分子量: 418.403
• InChiKey: HRVGAPBRUYRVTJ-SFHVURJKSA-N

反应信息

• 作为产物：
  描述：

  2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid dibutyryloxymethyl ester 在 水 作用下， 以 异丙醚 为溶剂， 反应 24.0h， 生成 (R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid monobutyryloxymethyl ester 、 (S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid monobutyryloxymethyl ester
  参考文献：
  名称：

  Drastic solvent effect on lipase-catalyzed enantioselective hydrolysis of prochiral 1,4-dihydropyridines

  摘要：

  Two enantiomers of 1,4-dihydropyridine compounds have been obtained with high enantiomeric purity by lipase-catalyzed hydrolysis in organic solvent saturated with water. Enantioselectivity of this reaction is dependent on the solvent used.

  DOI：

  10.1016/s0040-4039(00)60861-4