[11-(2-Hydroxy-3-methyl-phenyl)-undecyl]-carbamic acid tert-butyl ester | 141920-38-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: [11-(2-Hydroxy-3-methyl-phenyl)-undecyl]-carbamic acid tert-butyl ester
• CAS: 141920-38-9
• 化学式: C₂₃H₃₉NO₃
• 分子量: 377.568
• InChiKey: KSYZEYRGMPJTRE-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  [11-(2-Hydroxy-3-methyl-phenyl)-undecyl]-carbamic acid tert-butyl ester 在 N-甲基咪唑 、 三氟化硼乙醚 、 三氟乙酸 作用下， 以 甲醇 、 二氯甲烷 、 乙酸乙酯 为溶剂， 生成 Acetic acid (4Z,6E)-3-methyl-2-oxo-azacyclooctadeca-4,6-dien-7-yl ester
  参考文献：
  名称：

  Photolactamization: A Novel Synthetic Entry into Large Ring-Sized Lactams

  摘要：

  Diene ketenes smoothly accessible by photochemical ring cleavage of omicron-quinol acetates, in the presence of primary or secondary amines afford the corresponding amides. In an intramolecular version of this reaction macrocyclic lactams of type A are produced, if aminoalkylated omicron-quinol acetates of type C are used as photo reactants. These photo reactants are available on acid mediated removal of the Boc-protecting group from Wessely acetoxylation products of type D, easily formed via compounds of type E from aminoalkylated phenols of type F.

  DOI：

  10.1016/0040-4039(92)88118-o
• 作为产物：
  描述：

  Methanesulfonic acid 11-(2-hydroxy-3-methyl-phenyl)-undecyl ester 在 lithium aluminium tetrahydride 、 sodium azide 作用下， 生成 [11-(2-Hydroxy-3-methyl-phenyl)-undecyl]-carbamic acid tert-butyl ester
  参考文献：
  名称：

  Photolactamization: A Novel Synthetic Entry into Large Ring-Sized Lactams

  摘要：

  Diene ketenes smoothly accessible by photochemical ring cleavage of omicron-quinol acetates, in the presence of primary or secondary amines afford the corresponding amides. In an intramolecular version of this reaction macrocyclic lactams of type A are produced, if aminoalkylated omicron-quinol acetates of type C are used as photo reactants. These photo reactants are available on acid mediated removal of the Boc-protecting group from Wessely acetoxylation products of type D, easily formed via compounds of type E from aminoalkylated phenols of type F.

  DOI：

  10.1016/0040-4039(92)88118-o