Diaethyl-4,4'-methylen-di(N-methylcarbanilat) | 63896-11-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Diaethyl-4,4'-methylen-di(N-methylcarbanilat)
• 英文别名: diethyl 4,4'-methylenedi(N-methylcarbanilate)；ethyl N-[4-[[4-[ethoxycarbonyl(methyl)amino]phenyl]methyl]phenyl]-N-methylcarbamate
• CAS: 63896-11-7
• 化学式: C₂₁H₂₆N₂O₄
• 分子量: 370.448
• InChiKey: IRILFWAYVPQTPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  59.1
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• METHOD FOR PREPARING ISOCYANATES BY LIQUID-PHASE THERMAL CRACKING
  申请人：DENG Youquan

  公开号：US20110021810A1

  公开（公告）日：2011-01-27

  The present invention discloses a method for preparing isocyanates by liquid-phase catalytic thermal cracking. In this method, in a reaction-rectification thermal cracking reactor, using a catalyst composition comprising a superfine powder metal oxide catalyst and an ionic liquid, an alkyl or aryl dialkylurethane, or multialkylurethane being a reactant is liquid-phase thermal cracked for a reaction time of 0.5-3 h under a reaction temperature of 160-220° C. and an absolute pressure of 1000-8000 Pa so as to prepare the corresponding isocyanate. The invention has the characteristics of low thermal cracking temperature, high yield of target products, relatively simple reaction apparatus and good universality for substrates (the yields of HDI, MDI, TDI, HMDI, NDI and IPDI or the like are all >85%) and the like.

  本发明公开了一种通过液相催化热裂解制备异氰酸酯的方法。在该方法中，在反应-精馏热裂解反应器中，使用包括超细粉末金属氧化物催化剂和离子液体的催化剂组合物，以烷基或芳基二烷基脲或多烷基脲为反应物，在反应温度为160-220°C、绝对压力为1000-8000帕的条件下，液相热裂解反应时间为0.5-3小时，以制备相应的异氰酸酯。该发明具有热裂解温度低、目标产品产率高、反应装置相对简单、对底物具有良好的普适性（HDI、MDI、TDI、HMDI、NDI和IPDI等产率均>85%）等特点。
• Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases
  申请人：——

  公开号：US20030162995A1

  公开（公告）日：2003-08-28

  Integrated process for the preparation of aromatic isocyanates comprising: the reaction between an aromatic amine and an organiccarbonate in the presence of a catalyst selected from organic and inorganic salts of a metal selected from Zn, Sn, Pb, Cu; the removal of the catalyst; the passivation of the quantity of residual metal in the urethane formed in step a); the removal of the organic solvent and its optional recycling to step a) of the reaction; the evaporation of the aromatic urethane with partial pyrolysis; the complete pyrolysis of the urethane in gas phase; the recovery of the isocyanate.

  制备芳香族异氰酸酯的综合工艺，包括在选自 Zn、Sn、Pb、Cu 金属的有机盐和无机盐的催化剂存在下，芳香胺和有机碳酸盐发生反应；除去催化剂；钝化步骤 a) 中形成的氨基甲酸乙酯中的残余金属量；除去有机溶剂，并选择将其回收至反应步骤 a)；蒸发芳香氨基甲酸乙酯并进行部分热解；气相中的氨基甲酸乙酯完全热解；回收异氰酸酯。
• INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES
  申请人：Enichem S.p.A.

  公开号：EP1255728A1

  公开（公告）日：2002-11-13
• US4069240A
  申请人：——

  公开号：US4069240A

  公开（公告）日：1978-01-17
• US6992214B2
  申请人：——

  公开号：US6992214B2

  公开（公告）日：2006-01-31