N-allyl-N-(2-oxo-2H-1-benzopyran-6-yl)ethenesulfonamide | 1620758-81-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: N-allyl-N-(2-oxo-2H-1-benzopyran-6-yl)ethenesulfonamide
• CAS: 1620758-81-7
• 化学式: C₁₄H₁₃NO₄S
• 分子量: 291.328
• InChiKey: MRMOAGYVRAXFRC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.26
• 重原子数：
  20.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  67.59
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  N-allyl-N-(2-oxo-2H-1-benzopyran-6-yl)ethenesulfonamide 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 甲苯 为溶剂， 反应 1.0h， 以95%的产率得到2-(2-oxo-2H-1-benzopyran-6-yl)-2,3-dihydroisothiazole 1,1-dioxide
  参考文献：
  名称：

  Synthesis of Sultams by Ring-Closing Metathesis

  摘要：

  Synthesis of a series of five-membered sultams containing different hetero- or carbocycles were obtained in good to excellent yields by ring-closing metathesis (RCM) reaction. Many sultams were precipitated from the reaction mixture and they were easily separated by filtration without further purification.

  DOI：

  10.1055/s-0033-1340360
• 作为产物：
  描述：

  2-氯乙烷磺酰氯 、 6-(烯丙基氨基)-2H-色烯-2-酮 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.25h， 以90%的产率得到N-allyl-N-(2-oxo-2H-1-benzopyran-6-yl)ethenesulfonamide
  参考文献：
  名称：

  Synthesis of Sultams by Ring-Closing Metathesis

  摘要：

  Synthesis of a series of five-membered sultams containing different hetero- or carbocycles were obtained in good to excellent yields by ring-closing metathesis (RCM) reaction. Many sultams were precipitated from the reaction mixture and they were easily separated by filtration without further purification.

  DOI：

  10.1055/s-0033-1340360